Diisopropyl (2S,3S)-2,3-dihydroxysuccinate(CAS: 62961-64-2)

Diisopropyl (2S,3S)-2,3-dihydroxysuccinate is a white crystalline solid with a molecular weight of approximately 256.44 g/mol. It has a solubility of about 1.5 g/L in water at 25°C. Chemically, it exhibits reactivity typical of diol functionalities and succinic acid derivatives, making it suitable for various synthetic transformations.

Diisopropyl (2S,3S)-2,3-dihydroxysuccinate is usually synthesized via a multi-step process involving the reaction of diisopropyl succinyl chloride with sodium hydroxide to form the sodium salt, which is then converted to the diisopropyl ester via esterification. This process requires careful control of reaction conditions to achieve high yield and selectivity.

Diisopropyl (2S,3S)-2,3-dihydroxysuccinate finds applications in pharmaceuticals for drug synthesis, in polymers for modifying properties, and in sensors for detecting specific chemical species. It is also used in semiconductor manufacturing for its reactivity and stability.

When handling Diisopropyl (2S,3S)-2,3-dihydroxysuccinate, it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be carried out in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up according to standard laboratory procedures, and safety data sheets (SDS) should be consulted for detailed handling guidelines.