7-Bromoquinoline-3-carbaldehyde(CAS: 745830-24-4)

7-Bromoquinoline-3-carbaldehyde (CAS: 745830-24-4) is a crystalline solid with a molecular weight of approximately 235.06 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound is known for its high reactivity, particularly towards nucleophiles due to the presence of the carbonyl group and the electron-withdrawing bromine atom. It is often used in organic synthesis as a key intermediate.

7-Bromoquinoline-3-carbaldehyde (CAS: 745830-24-4) is typically synthesized through the bromination of quinoline-3-carbaldehyde using N-bromosuccinimide (NBS) in the presence of a photoinitiator. This method provides good yield and selectivity. Alternatively, it can be synthesized through a reaction of quinoline with bromine in the presence of an appropriate base such as sodium hydroxide.

7-Bromoquinoline-3-carbaldehyde (CAS: 745830-24-4) is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various drugs and organic compounds. Additionally, it finds applications in the development of sensors and semiconductors due to its unique chemical properties.

When handling 7-Bromoquinoline-3-carbaldehyde (CAS: 745830-24-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to bromine vapor. In case of spills, neutralize any bromine-containing compounds and clean up according to the Material Safety Data Sheet (MSDS). Always refer to the latest SDS for specific safety guidelines.