1H-Pyrrole-3-carbonitrile(CAS: 7126-38-7)

1H-Pyrrole-3-carbonitrile (CAS: 7126-38-7) is a crystalline compound with a molecular weight of 107.08 g/mol. It has a low solubility in water (0.2 g/L at 25°C) but is soluble in organic solvents like ethanol and acetone. The compound is moderately reactive, particularly when exposed to acid or base conditions, and can undergo nucleophilic substitution reactions.

1H-Pyrrole-3-carbonitrile is typically synthesized via the reaction of pyrrole with cyanogen chloride or by the cyanation of pyrrole using sodium cyanide. The process involves heating under basic conditions, with high yields (up to 90%) and good selectivity.

1H-Pyrrole-3-carbonitrile (CAS: 7126-38-7) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those with pyrrole-based structures. It is also utilized in the polymer industry for the production of speciality polymers, and in the electronics industry for the fabrication of semiconductor materials.

Handling 1H-Pyrrole-3-carbonitrile (CAS: 7126-38-7) requires adherence to safety guidelines. It should be stored in a cool, dry place away from oxidizing agents. PPE such as gloves, goggles, and lab coats should be worn. Spills should be cleaned up with appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed information on handling and emergency procedures.