4-Fluorobenzoyl chloride(CAS: 403-43-0)

4-Fluorobenzoyl chloride is an aromatic acyl chloride compound with the chemical formula C8H6ClFO2. It features a fluorine atom at the para position on a benzoyl chloride group, making it reactive and useful in organic synthesis. This compound is a colorless liquid with a sharp odor, highly soluble in organic solvents, and sensitive to moisture and light.

4-Fluorobenzoyl chloride is primarily used in pharmaceuticals for synthesizing fluorinated drugs and intermediates. It also serves in industrial applications such as polymer production and dye manufacturing. In research, it acts as an acylating agent for creating fluorine-containing compounds, including agrochemicals and organic materials.

4-Fluorobenzoyl chloride is toxic and requires careful handling. It may cause skin and eye irritation, respiratory issues, and is harmful if ingested. Safety measures include wearing protective gloves, goggles, and a lab coat, using fume hoods, and adhering to OSHA and EPA guidelines. Always follow proper disposal protocols to minimize environmental impact.

4-Fluorobenzoyl chloride should be stored in a cool, dry place (ideally 2-8°C), sealed in airtight containers to prevent moisture and contamination. It must be kept away from light and incompatible materials. Storage in a well-ventilated area is essential, and it is recommended to use a fume hood to ensure stability and safety.