2-Methyl-2-propanyl 3-(hydroxymethyl)-1-pyrrolidinecarboxylate(CAS: 114214-69-6)

2-Methyl-2-propanyl 3-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 114214-69-6) is a colorless or white crystalline solid. It has a molecular weight of approximately 224.3 g/mol and a solubility of about 1.5 g/L in water. This compound is moderately reactive, particularly towards nucleophiles and bases. It is poorly soluble in water but has good solubility in organic solvents like ethanol and acetonitrile.

2-Methyl-2-propanyl 3-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 114214-69-6) is typically synthesized via the reaction of 2-methylpropanoyl chloride with 1-hydroxy-3-(2-hydroxyethyl)pyrrolidine. This process involves the use of anhydrous conditions and anhydrous solvents to minimize side reactions. The reaction is catalyzed by a Lewis acid and proceeds with good regioselectivity, yielding a product with high purity.

2-Methyl-2-propanyl 3-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 114214-69-6) is utilized in the pharmaceutical industry for the synthesis of various drug candidates. It also finds applications in the polymer industry for the modification of polymer chains. Additionally, this compound is used in the development of sensors and semiconductors due to its unique chemical properties.

When handling 2-Methyl-2-proanyl 3-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 114214-69-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure that the handling is conducted in a well-ventilated fume hood to minimize exposure to vapors. Spills should be cleaned up using absorbent materials, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for specific handling and disposal recommendations.