Gilteritinib hemifumarate(CAS: 1254053-84-3)

CAS Number
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Basic Information
Molecular Formula
C62H92N16O10
Molecular Weight
1221.5 g/mol
Chemical Identifiers
SMILES
OC(=O)/C=C/C(=O)O.COc1cc(ccc1N1CCC(CC1)N1CCN(CC1)C)Nc1nc(NC2CCOCC2)c(nc1C(=O)N)CC.COc1cc(ccc1N1CCC(CC1)N1CCN(CC1)C)Nc1nc(NC2CCOCC2)c(nc1C(=O)N)CC
InChIKey
UJOUWHLYTQFUCU-WXXKFALUSA-N
Database References
MDL Number
MFCD28386208
FAQ
Gilteritinib hemifumarate is a prodrug that is converted to gilteritinib, an inhibitor of the FLT3 receptor tyrosine kinase. It is used in the treatment of acute myeloid leukemia (AML) with a FLT3 mutation.
Gilteritinib hemifumarate is primarily used in the treatment of patients with acute myeloid leukemia (AML) who have a mutation in the FLT3 gene. It is also used in clinical trials for the treatment of other hematologic malignancies.
Gilteritinib hemifumarate is generally considered safe when used as directed. However, it can cause side effects such as nausea, diarrhea, fatigue, and certain blood disorders. Patients should follow medical advice to minimize risks.
Gilteritinib hemifumarate should be stored at room temperature (15-30°C) and protected from light. It should be kept in a tightly closed container and away from moisture and heat to maintain its effectiveness and stability.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
shenlinxing@macklin.cn
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15221275939
Telephone
021-50706066
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021-50706099
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