(9S)-9-Amino-9-deoxoerythromycin(CAS: 26116-56-3)

(9S)-9-Amino-9-deoxoerythromycin, CAS 26116-56-3, is a semi-synthetic antibiotic with a molecular weight of approximately 685.81 g/mol. It is a white to off-white crystalline powder. It is sparingly soluble in water but soluble in organic solvents like methanol. The compound exhibits moderate reactivity, particularly towards nucleophilic substitution reactions. It is stable to heat and light but should be stored in a cool, dry place to prevent degradation.

(9S)-9-Amino-9-deoxoerythromycin is synthesized through a multi-step process starting from erythromycin or deoxoerythromycin. The key steps include chemical modifications such as demethylation, reduction, and amino substitution. The synthesis typically requires the use of catalysts like palladium on carbon and specific reagents, with good selectivity and yield. The final step involves the introduction of the amino group at position 9, followed by derivatization to obtain the desired product.

(9S)-9-Amino-9-deoxoerythromycin is primarily used in the pharmaceutical industry as a precursor to antibiotics. It is also of interest in the chemical research field for its biological activity and potential use in developing new antibiotics. While not as widely used, it may have applications in other industries such as agriculture and biotechnology for its antimicrobial properties.

When handling (9S)-9-Amino-9-deoxoerythromycin (CAS: 26116-56-3), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be carried out in a fume hood to minimize inhalation risks. Spills should be immediately contained and disposed of according to safety protocols. Always refer to the Safety Data Sheet (SDS) for detailed guidance and emergency procedures. The compound should be stored in a cool, dry place away from heat sources and oxidizers to prevent degradation and ensure safety.