4-Bromo-2,3-difluoroaniline(CAS: 112279-72-8)

4-Bromo-2,3-difluoroaniline (CAS: 112279-72-8) is a white crystalline solid with a molecular weight of approximately 228.02 g/mol. It has a low solubility in water (0.1 g/100 mL at 25°C) and is highly soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly in nucleophilic substitution and electrophilic aromatic substitution reactions.

4-Bromo-2,3-difluoroaniline (CAS: 112279-72-8) is typically synthesized via a multi-step process involving the bromination of 2,3-difluoroaniline followed by a nitration step. The synthesis involves the use of catalysts such as iron(III) chloride and concentrated sulfuric acid, and the reaction is carried out under anhydrous conditions to achieve high yield and selectivity.

4-Bromo-2,3-difluoroaniline (CAS: 112279-72-8) is used in various industries, including pharmaceuticals, where it serves as a key intermediate for the synthesis of drugs. It is also utilized in the production of dyes and pigments, as well as in the development of sensors and semiconductors.

When handling 4-Bromo-2,3-difluoroaniline (CAS: 112279-72-8), safety precautions include wearing appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a well-ventilated area and handled in a fume hood to minimize exposure. In case of a spill, it should be cleaned up using appropriate methods as outlined in the Material Safety Data Sheet (MSDS/SDS).