2-Methoxy-3-nitropyridine(CAS: 20265-35-4)

2-Methoxy-3-nitropyridine is a crystalline solid with a molecular weight of approximately 186.12 g/mol. It is slightly soluble in water but more soluble in organic solvents such as ethanol and acetone. Chemically, it is reactive towards reducing agents and can undergo substitution and reduction reactions. Its physical properties include a melting point of around 124-126°C.

2-Methoxy-3-nitropyridine is typically synthesized by nitration of 2-methoxypyridine followed by reduction of the nitro group. Common methods include catalytic reduction using hydrogen gas over a palladium-on-carbon catalyst. The overall process yields a product with high purity and good selectivity.

2-Methoxy-3-nitropyridine is used in various industries, including pharmaceuticals for the synthesis of drug intermediates, polymer production for special chemical applications, and as a precursor in sensor and semiconductor manufacturing processes. Its versatile chemical properties make it valuable in these sectors.

When handling 2-Methoxy-3-nitropyridine, it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from direct sunlight and flammable materials. Always use a fume hood during preparation and disposal. Refer to the Safety Data Sheet (SDS) for detailed safety and handling instructions.