N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-hydroxy-O-methyl-L-tyrosine(CAS: 148515-78-0)

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-hydroxy-O-methyl-L-tyrosine (CAS: 148515-78-0) is a white crystalline solid with a molecular weight of approximately 535 g/mol. It is slightly soluble in water and moderately soluble in organic solvents. This compound is known for its stability and reactivity in esterification reactions. It is used as a chiral building block in the synthesis of pharmaceuticals and natural product analogues.

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-hydroxy-O-methyl-L-tyrosine (CAS: 148515-78-0) is synthesized through a multi-step process. Starting material is fluoren-9-ylmethanol, which undergoes acylation to form the fluoren-9-ylmethoxy carbonyl. This intermediate is then coupled with 2-hydroxy-O-methyl-L-tyrosine in the presence of a suitable catalyst to yield the desired product. The reaction typically provides high yield and good purity.

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-hydroxy-O-methyl-L-tyrosine (CAS: 148515-78-0) is primarily used in the pharmaceutical industry for the synthesis of chiral intermediates and drugs. It is also used in the research and development of natural product analogues and in various applications including polymers and sensors.

When handling N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-hydroxy-O-methyl-L-tyrosine (CAS: 148515-78-0), it is important to wear appropriate personal protective equipment (PPE), including gloves and eye protection. The compound should be stored in a cool, dry place away from sources of heat and light. In case of spills, they should be cleaned up immediately using appropriate safety measures, and the area should be ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.