Ethyl 2-((4-cyanophenyl)amino)acetate(CAS: 218168-58-2)

Ethyl 2-((4-cyanophenyl)amino)acetate (CAS: 218168-58-2) is a crystalline solid with a molecular weight of approximately 247.2 g/mol. It has a slight solubility in water and is more soluble in organic solvents like ethanol and acetone. This compound is moderately reactive, particularly in the presence of acidic or basic conditions. It can undergo hydrolysis and condensation reactions.

Ethyl 2-((4-cyanophenyl)amino)acetate (CAS: 218168-58-2) is typically synthesized by the reaction of 4-cyanophenylamine with ethyl acetoacetate using a mild base like sodium hydroxide as the catalyst. The reaction proceeds under reflux conditions, yielding a high yield of the target compound with good selectivity.

Ethyl 2-((4-cyanophenyl)amino)acetate (CAS: 218168-58-2) is used in the pharmaceutical industry for the synthesis of certain derivatives and intermediates. It is also utilized in the polymer industry for the development of functional polymers. Additionally, it has applications in the semiconductor industry for thin film production and in the sensor industry as a functional material.

When handling Ethyl 2-((4-cyanophenyl)amino)acetate (CAS: 218168-58-2), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Storage should be in a cool, dry place away from direct sunlight. Fume hoods should be used during synthesis to minimize inhalation exposure. In case of a spill, immediately clean up with appropriate absorbent materials and consult the Safety Data Sheet (SDS) for further instructions.