Preparation of pyridopyrazines through tandem Pd-catalyzed C–N/C–C coupling reactions of Ugi adducts
Literature Information
Publication Date
2023-11-23
DOI
10.1039/D3OB01768K
Impact Factor
3.876
Authors
Ahmad Takallou, Munir Al-Siyabi, Sulaiman Al-Shidhani, Yazdanbakhsh Lotfi Nosood, Azizollah Habibi, Alhajaj Almaani, Muhammad U. Anwar, Ahmed Al-Harrasi
View Original
Abstract
A Pd-catalyzed selective tandem cyclization of the Ugi adduct via Buchwald–Hartwig/C–H bond functionalization reactions has been reported. This sequence offers an interesting approach for synthesizing a wide range of pyrido[1,2-a]pyrazine-3,6-dione scaffolds under mild reaction conditions in moderate to excellent yields. The scope and limitations of the protocol are discussed.
Related Literature
Alternate cycles of CO2 storage and in situ hydrogenation to CH4 on Ni–Na2CO3/Al2O3: influence of promoter addition and calcination temperature
Alejandro Bermejo-López, Beñat Pereda-Ayo, José A. González-Marcos, Juan R. González-Velasco
2021-01-18
Paper
DOI: 10.1039/D0SE01677B
Highly efficient and stable perovskite solar cells produced by maximizing additive engineering
Linlin Qiu, Jiacheng Zou, Wei-Hsiang Chen, Lika Dong, Deqiang Mei, Jieqiong Wang, Pei-Cheng Jiang
2020-11-12
Paper
DOI: 10.1039/D0SE01498B
Ultrathin MoS2 wrapped N-doped carbon-coated cobalt nanospheres for OER applications
Ashish Gaur, Parrydeep K. Sachdeva, Rajinder Kumar, Takahiro Maruyama, Chandan Bera, Vivek Bagchi
2020-12-10
Paper
DOI: 10.1039/D0SE01543A
Enhanced OER performance of composite Co–Fe-based MOF catalysts via a one-pot ultrasonic-assisted synthetic approach
Fen Li, Jinxia Li, Lihui Zhou, Sheng Dai
2021-01-11
Paper
DOI: 10.1039/D0SE01750G
A facile preparation of PEO–LiClO4–fumed SiO2 composite solid-state electrolyte with improved electrochemical performance for lithium-metal batteries
Ruyan Lei, Yanping Yang, Chenjuan Yu, Yinsi Xu, Yuanzhuo Li, Jun Li
2021-01-28
Paper
DOI: 10.1039/D1SE00038A
Mechanisms of photoredox catalysts: the role of optical spectroscopy
Noufal Kandoth, Javier Pérez Hernández
2021-01-20
Review Article
DOI: 10.1039/D0SE01454K
D–A–π–A organic dyes with tailored green light absorption for potential application in greenhouse-integrated dye-sensitized solar cells
Alessio Dessì, Dimitris A. Chalkias, Stefania Bilancia, Aggeliki Karavioti, Elias Stathatos, Lorenzo Zani, Gianna Reginato
2021-01-15
Paper
DOI: 10.1039/D0SE01610A
A comparison of sizing methods for a long-term renewable hybrid system. Case study: Galapagos Islands 2031
A. Cano, Paul Arévalo, F. Jurado
2021-02-04
Paper
DOI: 10.1039/D1SE00078K
Correction: Using high-throughput virtual screening to explore the optoelectronic property space of organic dyes; finding diketopyrrolopyrrole dyes for dye-sensitized water splitting and solar cells
Isabelle Heath-Apostolopoulos, Diego Vargas-Ortiz, Liam Wilbraham, Kim E. Jelfs, Martijn A. Zwijnenburg
2021-02-10
Correction
DOI: 10.1039/D1SE90005F
Tungsten oxide-coated copper gallium selenide sustains long-term solar hydrogen evolution
David W. Palm, Christopher P. Muzzillo, Micha Ben-Naim, Imran Khan, Nicolas Gaillard
2020-12-08
Communication
DOI: 10.1039/D0SE00487A
You might also like
Compound Q&A
What regulatory guidelines apply to 4-Amino-3-bromophenol (CAS: 74440-80-5)?
4-Amino-3-bromophenol (CAS: 74440-80-5) falls under the classification of a haza...
74440-80-54-Amino-3-bromopheno...
Compound Q&A
How should (17beta)-3-Oxoestr-4-en-17-yl acetate (CAS: 1425-10-1) be stored?
(17beta)-3-Oxoestr-4-en-17-yl acetate should be stored in a cool, dry place away...
1425-10-1(17beta)-3-Oxoestr-4...
Compound Q&A
What are the physical and chemical properties of 2-[(2,2-Diethoxyethyl)disulfanyl]-1,1-diethoxyethane (CAS: 76505-71-0)?
2-[(2,2-Diethoxyethyl)disulfanyl]-1,1-diethoxyethane (CAS: 76505-71-0) is a colo...
76505-71-02-[(2,2-Diethoxyethy...
Compound Q&A
What is the market or research trend for 1-(β-D-ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine?
The market and research for 1-(β-D-ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-ami...
6736-58-91-(beta-D-Ribofurano...
Compound Q&A
How should waste containing Conjugated Estrogen (CAS: 12126-59-9) be handled?
Waste containing Conjugated Estrogen (CAS: 12126-59-9) should be collected and d...
12126-59-9Conjugated Estrogen
Compound Q&A
What is the market or research trend for Bis(2,2,2-trifluoroethyl) (methoxycarbonylmethyl)phosphonate?
The market for Bis(2,2,2-trifluoroethyl) (methoxycarbonylmethyl)phosphonate (CAS...
88738-78-7Bis(2,2,2-trifluoroe...
Compound Q&A
Are there alternatives to 3,4'-Di-O-methylellagic acid (CAS: 57499-59-9) in synthesis?
There are several alternatives to 3,4'-Di-O-methylellagic acid (CAS: 57499-59-9)...
57499-59-93,4'-Di-O-methylella...
Compound Q&A
What regulatory guidelines apply to 2-Chloro-N,N-dimethylpyridin-4-amine (CAS: 59047-70-0)?
2-Chloro-N,N-dimethylpyridin-4-amine (CAS: 59047-70-0) is regulated under the Gl...
59047-70-02-Chloro-N,N-dimethy...
Compound Q&A
What is cerium(3+);oxygen(2-);vanadium(5+) (CAS: 13597-19-8)?
Cerium(3+);oxygen(2-);vanadium(5+) (CAS: 13597-19-8) is a complex inorganic comp...
13597-19-8cerium(3+);oxygen(2-...
Compound Q&A
Is 7-Chloro-1-iodoisoquinoline (CAS: 1203579-27-4) safe?
7-Chloro-1-iodoisoquinoline (CAS: 1203579-27-4) is generally considered safe whe...
1203579-27-47-Chloro-1-iodoisoqu...
Source Journal
Organic & Biomolecular Chemistry
CiteScore:
3.4
Self-citation Rate:
10.3%
Articles per Year:
1041
Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.
Recommended Compounds
![9-Ethyl-3-{(E)-[ethyl(2-methylphenyl)hydrazono]methyl}-9H-carbazole structure](https://static.chemtradehub.com/structs/127/1274948-12-7-301f.webp "9-Ethyl-3-{(E)-[ethyl(2-methylphenyl)hydrazono]methyl}-9H-carbazole structure")
9-Ethyl-3-{(E)-[ethyl(2-methylphenyl)hydrazono]methyl}-9H-carbazole
CAS Number:
1274948-12-7
Molecular Formula:
C24H25N3
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.