What is missing in autonomous discovery: open challenges for the community
Literature Information
Sterling G. Baird, Keith A. Brown, Stuart I. Campbell, Orion A. Cohen, Rebecca L. Davis, Navid Haghmoradi, Howie Joress, Nicole Jung, Ha-Kyung Kwon, Gabriella Pizzuto, Jacob Rintamaki, Casper Steinmann, Luca Torresi
Self-driving labs (SDLs) leverage combinations of artificial intelligence, automation, and advanced computing to accelerate scientific discovery. The promise of this field has given rise to a rich community of passionate scientists, engineers, and social scientists, as evidenced by the development of the Acceleration Consortium and recent Accelerate Conference. Despite its strengths, this rapidly developing field presents numerous opportunities for growth, challenges to overcome, and potential risks of which to remain aware. This community perspective builds on a discourse instantiated during the first Accelerate Conference, and looks to the future of self-driving labs with a tempered optimism. Incorporating input from academia, government, and industry, we briefly describe the current status of self-driving labs, then turn our attention to barriers, opportunities, and a vision for what is possible. Our field is delivering solutions in technology and infrastructure, artificial intelligence and knowledge generation, and education and workforce development. In the spirit of community, we intend for this work to foster discussion and drive best practices as our field grows.
Related Literature
Regiochemical control of the catalytic asymmetric hydroboration of 1,2-diarylalkenes
Antonia Black, John M. Brown, Christophe Pichon
DOI: 10.1039/B508292G
Facile and reproducible syntheses of bis(dialkylselenophosphenyl)-selenides and -diselenides: X-ray structures of (iPr2PSe)2Se, (iPr2PSe)2Se2 and (Ph2PSe)2Se
Chinh Q. Nguyen, Adekunle Adeogun, Mohammad Afzaal, Mohammad A. Malik, Paul O'Brien
DOI: 10.1039/B603197H
Synthesis of organic–inorganic hybrid mesoporous tin oxophosphate in the presence of anionic surfactant
Masahiro Fujiwara, Masahiko Matsukata
DOI: 10.1039/B508589F
Synthesis, structure, and olefinpolymerization with nickel(ii) N-heterocyclic carbene enolates
Benjamin E. Ketz, Xavier G. Ottenwaelder, Robert M. Waymouth
DOI: 10.1039/B511202H
Simple transformation of crystalline chiral natural anions to liquid medium and their use to induce chirality
Luís C. Branco, Pedro M. P. Gois, Nuno M. T. Lourenço, Vanya B. Kurteva, Carlos A. M. Afonso
DOI: 10.1039/B600816J
Supramolecular cruciforms
Warren W. Gerhardt, Anthony J. Zucchero, James N. Wilson, Clinton R. South, Uwe H. F. Bunz, Marcus Weck
DOI: 10.1039/B602087A
Insulated conducting polymers: manipulating charge transport using supramolecular complexes
Phoebe H. Kwan, Timothy M. Swager
DOI: 10.1039/B508399K
An electrochemical/photochemical information processing system using a monolayer-functionalized electrode
Ronan Baron, Avital Onopriyenko, Eugenii Katz, Oleg Lioubashevski, Itamar Willner, Sheng Wang, He Tian
DOI: 10.1039/B518378B
Evidence for C–C bond cleavage by H2O2 in a mesoporous CMK-5 type carbon at room temperature
An-Hui Lu, Wen-Cui Li, Nelli Muratova, Bernd Spliethoff, Ferdi Schüth
DOI: 10.1039/B509300G
You might also like
What are the main uses of 1H-Indazole-6-carbonitrile (CAS: 141290-59-7)?
1H-Indazole-6-carbonitrile finds applications in pharmaceuticals, where it serve...
How should waste containing Dioctyl (2E)-2-butenedioate (CAS: 2997-85-5) be handled?
Waste containing Dioctyl (2E)-2-butenedioate (CAS: 2997-85-5) should be collecte...
What industries use Sodium [(1,2-benzoxazol-3-ylmethyl)sulfonyl]azanide (CAS: 68291-98-5)?
Sodium [(1,2-benzoxazol-3-ylmethyl)sulfonyl]azanide is primarily used in pharmac...
Are there alternatives to Dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-pyridinedicarboxylate (CAS: 741709-66-0) in synthesis?
Dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-pyridinedicarboxyla...
How should waste containing 2-Fluoro-6-hydrazinopyridine (CAS: 80714-39-2) be handled?
Waste containing 2-Fluoro-6-hydrazinopyridine (CAS: 80714-39-2) should be manage...
What is 6-Formyl-2-pyridinecarboxylic acid (CAS: 499214-11-8)?
6-Formyl-2-pyridinecarboxylic acid is an organic compound with the molecular for...
What is the market or research trend for 3-(3,4-dimethoxyphenyl)-2,5-dimethyl-N-(2-morpholin-4-ylethyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS: 900874-91-1)?
Research trends for this compound indicate a focus on its potential applications...
How is 9H-Tribenzo[b,d,f]azepine (CAS: 29875-73-8) typically synthesized?
9H-Tribenzo[b,d,f]azepine is typically synthesized via a multi-step process invo...
How is 1-Cyclopropyl-7-ethoxy-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 1797982-51-4) typically synthesized?
1-Cyclopropyl-7-ethoxy-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxyli...
How should waste containing Methyl 3-oxo-1,2,3,4-tetrahydro-6-quinoxalinecarboxylate (CAS: 671820-52-3) be handled?
Waste containing Methyl 3-oxo-1,2,3,4-tetrahydro-6-quinoxalinecarboxylate (CAS: ...















