Iridium-catalyzed selective arylation of B(6)–H of 3-aryl-o-carboranes with arylboronic acid via direct B–H activation
Literature Information
Han-Bo Yang, Yan Guo, Ke Cao, Qi-Jia Jiang, Chao-Chao Teng, Dao-Yong Zhu, Shao-Hua Wang
This work discloses an iridium-catalyzed selective arylation of B(6)–H of 3-Ar-o-carboranes with arylboronic acid via direct B–H activation for the first time. A series of unsymmetric and symmetric 3,6-diaryl-o-carboranes decorated with diverse active groups have been synthesized with moderate to excellent yields under mild conditions. This work offers an efficient approach for selective arylation of B(6)–H with arylboronic acid and has important value for selective functionalization of o-carboranes.
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