Unprecedented Barbier-type reactions catalysed by titanocene(iii)

Literature Information

Publication Date 2004-10-05
DOI 10.1039/B411173G
Impact Factor 6.222
Authors

Antonio Rosales, Juan L. Oller-López, José Justicia, Andreas Gansäuer, J. Enrique Oltra, Juan M. Cuerva


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Abstract

Selective Barbier-type allylations, benzylations and propargylations of aldehydes and ketones can be carried out under extremely mild conditions employing titanocene(III) complexes as catalysts. In this way, chiral titanocene catalysts provided yields ranging from 50–80% of optically active products.

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