Peptide coupling using recyclable bicyclic benziodazolone

Literature Information

Publication Date 2023-12-18
DOI 10.1039/D3CC04431A
Impact Factor 6.222
Authors

Daigo Uehara, Sota Adachi, Akira Tsubouchi, Yohei Okada, Viktor V. Zhdankin, Akira Yoshimura, Akio Saito


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Abstract

We report a greener peptide coupling using bicyclic benziodazolone and triarylphosphine as coupling reagents. Bicyclic benziodazolone also works as a base and can be recovered as the corresponding iodine(I) compound after use, which can be converted to the original iodine(III) reagent by electrolytic oxidation.

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Chemical Communications

Chemical Communications
CiteScore: 8.6
Self-citation Rate: 4.7%
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ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

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