Recent advances in catalytic enantioselective direct C–H bond functionalization of electron-deficient N-containing heteroarenes
Literature Information
Publication Date
2021-09-22
DOI
10.1039/D1QO01223A
Impact Factor
5.281
Authors
Xiao-Lan Liu, Luo-Bin Jiang, Mu-Peng Luo, Zhi Ren, Shou-Guo Wang
View Original
Abstract
Catalytic enantioselective direct C–H bond functionalization of electron-deficient N-containing heteroarenes represents one of the most straightforward and powerful protocols to construct diverse enantioenriched highly functionalized N-heteroarene products. Efficient catalytic systems and a variety of strategies for highly chemo- and stereoselective C–H functionalization of electron-deficient N-containing heteroarenes have been developed over the past few decades. This review summarized the rapid progress in the catalytic asymmetric C–H functionalization of N-containing heteroarenes and discussed the challenges and potential of the field in the current stage.
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Organic Chemistry Frontiers
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