Recent advances in annulation reactions based on zwitterionic π-allyl palladium and propargyl palladium complexes

Literature Information

Publication Date 2021-04-08
DOI 10.1039/D1QO00273B
Impact Factor 5.281
Authors

Ben Niu, Yin Wei


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Abstract

In the past few years, Pd-catalyzed annulation reactions through zwitterionic π-allyl palladium intermediates have been extensively investigated. Meanwhile, zwitterionic π-allyl palladium and propargyl palladium have also been successfully demonstrated to be a vital and versatile synthon for the construction of carbocyclic and heterocyclic compounds, which include both structural scaffolds used in the pharmaceutical industry and novel heterocyclic skeletons with potential biological appeal. This review highlights representative advances in organic synthesis based on zwitterionic π-allyl palladium and propargyl palladium.

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Organic Chemistry Frontiers

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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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