Cucurbit[8]uril-based supramolecular hydrogels for biomedical applications
Literature Information
Publication Date
2021-03-10
DOI
10.1039/D1MD00019E
Impact Factor
0
Authors
Zeyu Wang, Mingju Shui, Ian W. Wyman, Qing-Wen Zhang, Ruibing Wang
View Original
Abstract
As a member of the cucurbit[n]uril family (where n denotes the number of glycoluril units), cucurbit[8]uril (CB[8]) possesses a large cavity volume and is able to accommodate two guests simultaneously. Therefore, CB[8] has been adapted as a dynamic noncovalent crosslinker to form various supramolecular hydrogels. These CB[8]-based hydrogels have been investigated for various biomedical applications due to their good biocompatibility and dynamic properties afforded by host–guest interactions. In this review, we summarize the hydrogels that have been dynamically fabricated via supramolecular crosslinking of polymers by CB[8] reported during the past decade, and discuss their design principles, innovative applications in biomedical science and their future prospects.
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Source Journal
Recommended Compounds
8-Methyl-2-pyridin-4-ylquinoline-4-carboxylic acid
CAS Number:
107027-42-9
Molecular Formula:
C16H12N2O2
![2-Methyl-2-propanyl [2-(2-oxa-6-azaspiro[3.3]hept-6-yl)ethyl]carbamate structure](https://static.chemtradehub.com/structs/141/1415562-38-7-c0a4.webp "2-Methyl-2-propanyl [2-(2-oxa-6-azaspiro[3.3]hept-6-yl)ethyl]carbamate structure")
2-Methyl-2-propanyl [2-(2-oxa-6-azaspiro[3.3]hept-6-yl)ethyl]carbamate
CAS Number:
1415562-38-7
Molecular Formula:
C12H22N2O3
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