Xanthanoltrimer A–C: three xanthanolide sesquiterpene trimers from the fruits of Xanthium italicum Moretti isolated by HPLC-MS-SPE-NMR
Literature Information
Publication Date
2021-01-26
DOI
10.1039/D0QO01541E
Impact Factor
5.281
Authors
Jiang Fu, Ya-Nan Wang, Shuang-Gang Ma, Li Li, Xiao-Jing Wang, Yong Li, Yun-Bao Liu, Jing Qu, Shi-Shan Yu
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Abstract
Xanthanoltrimer A–C (1–3), three xanthanolide sesquiterpene trimers, were first isolated from the fruits of Xanthium italicum Moretti by high-performance liquid chromatography-mass spectrometry-solid phase extraction-nuclear magnetic resonance spectroscopy (HPLC-MS-SPE-NMR). The structures of 1–3 were characterized by a series of spectroscopic methods, NMR calculations and electronic circular dichroism (ECD). Moreover, the cytotoxic, antiviral, anti-inflammatory, and antioxidant activities of 1–3 were screened, but they did not show significant biological activity.
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Organic Chemistry Frontiers
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