Direct access to benzofuro[2,3-b]quinoline and 6H-chromeno[3,4-b]quinoline cores through gold-catalyzed annulation of anthranils with arenoxyethynes and aryl propargyl ethers
Literature Information
Manoj D. Patil, Rai-Shung Liu
This work reports a facile annulation of anthranils with aryloxyethynes or aryl propargyl ethers to construct useful benzofuro[2,3-b]quinoline and 6H-chromeno[3,4-b]quinoline frameworks, respectively; these heterocycles are not readily available from literature methods despite their biological significance. This high atom- and step-economy strategy is highlighted by a broad substrate scope. The reaction mechanism is proposed to proceed through sequential cyclizations among the oxyaryl group, gold carbene and benzaldehyde of the α-imino gold carbene intermediates.
Related Literature
Electrochemical ‘bubble swarm’ enhancement of ultrasonic surface cleaning
P. R. Birkin, D. G. Offin, C. J. B. Vian, T. G. Leighton
DOI: 10.1039/C5CP02933C
Thermotropic interface and core relaxation dynamics of liquid crystals in silica glass nanochannels: a dielectric spectroscopy study
Sylwia Całus, Lech Borowik, Andriy V. Kityk, Manfred Eich, Mark Busch, Patrick Huber
DOI: 10.1039/C5CP03039K
On the short circuit resilience of organic solar cells: prediction and validation
A. Jolt Oostra, Edsger C. P. Smits, Dago M. de Leeuw, Paul W. M. Blom
DOI: 10.1039/C5CP03156G
Distinguishing the roles of energy funnelling and delocalization in photosynthetic light harvesting
Ivan Kassal
DOI: 10.1039/C6CP00104A
Direct observation of structural properties and fluorescent trapping sites in macrocyclic porphyrin arrays at the single-molecule level
Sujin Ham, Ji-Eun Lee, Suhwan Song, Xiaobin Peng, Takaaki Hori, Naoki Aratani, Atsuhiro Osuka, Eunji Sim, Dongho Kim
DOI: 10.1039/C5CP06859B
Fundamental aspects in surface self-assembly: theoretical implications of molecular polarity and shape
Emilian Tuca, Irina Paci
DOI: 10.1039/C5CP04479K
Temperature-dependent nanomorphology–performance relations in binary iridium complex blend films for organic light emitting diodes
Young-Tae Kim, Young-Hoon Kim, Tae-Woo Lee
DOI: 10.1039/C5CP03436A
Half-metallic and magnetic properties in nonmagnetic element embedded graphitic carbon nitride sheets
Bo Meng, Wen-zhi Xiao, Ling-ling Wang, Li Yue, Song Zhang, Hong-yun Zhang
DOI: 10.1039/C5CP03794H
Exploiting orientation-selective DEER: determining molecular structure in systems containing Cu(ii) centres
Michael W. Jones, Thembanikosi G. Gaule, Michael J. McPherson, Jonathan R. Dilworth, Christiane R. Timmel
DOI: 10.1039/C5CP06096F
Activation of carbon dioxide by a terminal uranium–nitrogen bond in the gas-phase: a demonstration of the principle of microscopic reversibility
Phuong D. Dau, P. B. Armentrout, Maria C. Michelini, John K. Gibson
DOI: 10.1039/C6CP00494F
You might also like
What is 1-(2,4,6-Trifluorophenyl)ethanol (CAS: 1250113-83-7)?
1-(2,4,6-Trifluorophenyl)ethanol is an organic compound with the CAS number 1250...
Is 1-(2,4-Dimethoxybenzyl)-4-(hydroxymethyl)-2-pyrrolidinone (CAS: 919111-34-5) safe?
1-(2,4-Dimethoxybenzyl)-4-(hydroxymethyl)-2-pyrrolidinone (CAS: 919111-34-5) is ...
What are the physical and chemical properties of (7S,15R)-6β,15-Diacetoxy-7α,20-epoxy-7-hydroxykaura-2,16-dien-1-one (CAS: 51419-51-3)?
(7S,15R)-6β,15-Diacetoxy-7α,20-epoxy-7-hydroxykaura-2,16-dien-1-one is a crystal...
What regulatory guidelines apply to rac-ethyl (1r,4r)-4-hydroxycyclohexane-1-carboxylate, trans (CAS: 3618-04-0)?
The compound rac-ethyl (1r,4r)-4-hydroxycyclohexane-1-carboxylate, trans (CAS: 3...
What is the market or research trend for 2-(2,4-Difluorophenoxy)-3-nitropyridine (CAS: 175135-62-3)?
The market for 2-(2,4-Difluorophenoxy)-3-nitropyridine (CAS: 175135-62-3) is cur...
What are the main uses of 6-Diazo-5-oxo-L-norleucine (CAS: 157-03-9)?
The main uses of 6-Diazo-5-oxo-L-norleucine (CAS: 157-03-9) include research in ...
What precautions should be taken when handling 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (CAS: 173308-19-5)?
When handling 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (CAS: 173308-19-5), i...
How is 5-Methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS: 178488-37-4) typically synthesized?
5-Methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS: 178488-37-4) can be synthesi...
Are there alternatives to 2,4,6-Trihydroxyisophthalaldehyde (CAS: 4396-13-8) in synthesis?
There are alternative reagents that can be used in the synthesis of 2,4,6-Trihyd...
What is (2Z)-3-(5-Fluoro-1H-indol-3-yl)-2-sulfanylacrylic acid (CAS: 179461-52-0)?
(2Z)-3-(5-Fluoro-1H-indol-3-yl)-2-sulfanylacrylic acid is a chemical compound wi...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.











![2-Methyl-2-propanyl 1,6-diazaspiro[3.4]octane-6-carboxylate structure 2-Methyl-2-propanyl 1,6-diazaspiro[3.4]octane-6-carboxylate structure](https://static.chemtradehub.com/structs/115/1158749-79-1-81ee.webp)

![2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole structure 2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole structure](https://static.chemtradehub.com/structs/122/1226781-80-1-09d5.webp)
