Enantioselective aryl–aryl coupling facilitated by chiral binuclear gold complexes
Literature Information
Jonas Himmelstrup, Mikkel B. Buendia, Xing-Wen Sun, Søren Kramer
Herein, we report stoichiometric investigations embodying the first highly enantioselective aryl–aryl coupling facilitated by a gold complex. With up to 91% ee, this is the first demonstration of a transmetalation and C(sp2)–C(sp2) reductive elimination sequence with high enantioselectivity using a gold complex. The results offer a basis for development of enantioselective gold-catalyzed aryl–aryl coupling reactions.
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