Homopropargyl as a new recognition moiety of a fluorescent probe for detection of palladium in living cells

Literature Information

Publication Date 2019-07-15
DOI 10.1039/C9AY00844F
Impact Factor 2.896
Authors

Miao Chen, Xianhui Wang, Nannan Wang, Xin Ji, Jinling He, Jian Zhang


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Abstract

Palladium contamination has attracted widespread attention due to the toxicity and the wide use of palladium species. Consequently, development of convenient and effective methods for palladium detection is of great importance. Herein, a BODIPY-based fluorescent probe containing a meso homopropargyl ester substituent as a new recognition moiety for detection of Pd2+ was developed. The probe could be used to detect Pd2+ in acetonitrile/PBS buffer (1 : 99 v/v, 10 mM, pH 7.4) at 37 °C with high selectivity and sensitivity. The detection limit of probe 1 toward Pd2+ was estimated to be 50.8 nM. Furthermore, probe 1 was successfully applied for detection of Pd2+ in living cells, indicating good potential application prospects.

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Analytical Methods
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Analytical Methods welcomes early applications of new analytical and bioanalytical methods and technology demonstrating the potential for societal impact. We require that methods and technology reported in the journal are sufficiently innovative, robust, accurate, and compared to other available methods for the intended application. Developments with interdisciplinary approaches are particularly welcome. Systems should be proven with suitably complex and analytically challenging samples. We encourage developments within, but not limited to, the following technologies and applications: global health, point-of-care and molecular diagnostics biosensors and bioengineering drug development and pharmaceutical analysis applied microfluidics and nanotechnology omics studies, such as proteomics, metabolomics or glycomics environmental, agricultural and food science neuroscience biochemical and clinical analysis forensic analysis industrial process and method development

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