DDQ-mediated regioselective C–S bond formation: efficient access to allylic sulfides

Literature Information

Publication Date 2018-09-18
DOI 10.1039/C8QO00799C
Impact Factor 5.281
Authors

Chunsheng Li, Jianxiao Li, Chaowei Tan, Wanqing Wu, Huanfeng Jiang


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Abstract

A protocol for the synthesis of allylic sulfides from simple allylic hydrocarbons with thiophenol derivatives via a DDQ-mediated oxidative dehydrogenation strategy is described. This reaction possesses good functional group compatibility, broad substrate scope, and high atom- and step-economy. Moreover, the synthetic utility of this method can be highlighted by its application in the synthesis of versatile organo-sulfur compounds.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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