An enantioselective synthesis of α-alkylated pyrroles via cooperative isothiourea/palladium catalysis
Literature Information
W. Rush Scaggs, Toya D. Scaggs, Thomas N. Snaddon
Herein we describe the direct enantioselective Lewis base/Pd catalysed α-allylation of pyrrole acetic acid esters. This provides high isolated yields of highly enantioenriched products and exhibits broad reaction scope with respect to both reaction partners. The products can be readily elaborated in a manner which points towards potential applications in target directed synthesis.
Related Literature
Quantitative probing of subtle interactions among H-bonds in alpha hydroxy carboxylic acid complexes
Peifeng Su, Yong Xia, Zhijun Yang, Carl O. Trindle, Joseph L. Knee
DOI: 10.1039/C7CP03917D
Unravelling hydrogen bonding interactions of tryptamine–water dimer from neutral to cation
Zongyuan Liu, Carl O. Trindle, Quanli Gu, Wei Wu, Peifeng Su
DOI: 10.1039/C7CP03491A
First-principles investigation of H2S adsorption and dissociation on titanium carbide surfaces
Shiyan Wang, Xilin Zhang, Yanxing Zhang, Jianjun Mao
DOI: 10.1039/C7CP05756C
Modeling the impedance spectra of mixed conducting thin films with exposed and embedded current collectors
Jiapeng Liu
DOI: 10.1039/C7CP03703A
Redistribution of valence and conduction band states depending on the method of modification of SiO2 structure
A. S. Konashuk, E. O. Filatova
DOI: 10.1039/C7CP04914E
Exploring coherent electron excitation and migration dynamics by electron diffraction with ultrashort X-ray pulses
Kai-Jun Yuan, André D. Bandrauk
DOI: 10.1039/C7CP05067D
Elucidating the mechanism of MgB2 initial hydrogenation via a combined experimental–theoretical study
Keith G. Ray, Leonard E. Klebanoff, Jonathan R. I. Lee, Vitalie Stavila, Tae Wook Heo, Patrick Shea, Alexander A. Baker, Shinyoung Kang, Michael Bagge-Hansen, Yi-Sheng Liu, James L. White, Brandon C. Wood
DOI: 10.1039/C7CP03709K
Self-assembled bundled TiO2 nanowire arrays encapsulated with indium tin oxide for broadband absorption in plasmonic photocatalysis
Xingce Fan, Zhengwei Luo, Xiangyu Hou, Xiaozhi Yang, Teng Qiu, Paul K. Chu
DOI: 10.1039/C7CP04196A
You might also like
What is 3-Fluoro-2-methylbenzylamine (CAS: 771573-36-5)?
3-Fluoro-2-methylbenzylamine is an organic compound with the CAS number 771573-3...
Is Tert-butyl 2-(oxetan-3-ylidene)acetate (CAS: 1207175-03-8) safe?
Tert-butyl 2-(oxetan-3-ylidene)acetate is considered safe for its intended uses ...
What precautions should be taken when handling 4-Acetyl-2-fluorobenzonitrile (CAS: 214760-18-6)?
Proper personal protective equipment (PPE) such as gloves, goggles, and a lab co...
How is 2-Ethyl-4-methyl-1,3-thiazole (CAS: 15679-12-6) typically synthesized?
2-Ethyl-4-methyl-1,3-thiazole is commonly synthesized via the reaction of thiour...
How should 5',5''-([2,2'-Bithiophene]-5,5'-diyl)bis(([1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid)) (CAS: 1227780-71-3) be stored?
This compound should be stored in a cool, dry place away from direct sunlight an...
What regulatory guidelines apply to L-Lysine Acetate Salt (CAS: 52315-92-1)?
L-Lysine Acetate Salt (CAS: 52315-92-1) is subject to various regulatory guideli...
Is 6-Fluoro-3-hydroxy-2-pyrazinecarboxamide (CAS: 259793-96-9) safe?
6-Fluoro-3-hydroxy-2-pyrazinecarboxamide (CAS: 259793-96-9) is generally conside...
What are the physical and chemical properties of 1,1'-Sulfonylbis(1H-imidazole) (CAS: 7189-69-7)?
1,1'-Sulfonylbis(1H-imidazole) is a crystalline solid with a molecular weight of...
What industries use 4-methyl-7-nitro-1H-indole-3-carbonitrile (CAS: 289483-82-5)?
4-Methyl-7-nitro-1H-indole-3-carbonitrile (CAS: 289483-82-5) is primarily used i...
How should waste containing 5-Bromo-3-indolyl-beta-galactoside (CAS: 97753-82-7) be handled?
Waste containing 5-Bromo-3-indolyl-beta-galactoside (CAS: 97753-82-7) should be ...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.














