Direct defluorinative amidation–hydrolysis reaction of gem-difluoroalkenes with N,N-dimethylformamide, and primary and secondary amines
Literature Information
Biyun Wang, Xianghu Zhao, Qingyun Liu, Song Cao
A novel and efficient method for the synthesis of arylacetamides by the reactions of gem-difluoroalkenes with N,N-dialkylformamides, and primary and secondary amines with the assistance of KOtBu and water was developed.
Related Literature
Comprehensive mass analysis for chemical processes, a case study on l-Dopa manufacture
Tao Li, Xuan Li
DOI: 10.1039/C4GC00565A
Transitioning organic synthesis from organic solvents to water. What's your E Factor?
Bruce H. Lipshutz, Subir Ghorai
DOI: 10.1039/C4GC00503A
Sustainable chromatography (an oxymoron?)
Emily A. Peterson, Barry Dillon, Izzat Raheem, Paul Richardson, Daniel Richter, Rachel Schmidt, Helen F. Sneddon
DOI: 10.1039/C4GC00615A
Hydrothermal saline promoted grafting: a route to sulfonic acid SBA-15 silica with ultra-high acid site loading for biodiesel synthesis
C. Pirez, A. F. Lee, J. C. Manayil, C. M. A. Parlett, K. Wilson
DOI: 10.1039/C4GC01139B
Carbon-supported iron–ionic liquid: an efficient and recyclable catalyst for benzylation of 1,3-dicarbonyl compounds with alcohols
P. Moriel, A. B. García
DOI: 10.1039/C4GC00755G
Solvent-tuned hydrophobicity for faujasite-catalyzed cycloaddition of biomass-derived dimethylfuran for renewable p-xylene
Ruichang Xiong, Stanley I. Sandler, Dionisios G. Vlachos, Paul J. Dauenhauer
DOI: 10.1039/C4GC00727A
The vanadate adsorption on a mesoporous boehmite and its cleaner production application of chromate
DOI: 10.1039/C4GC00897A
New bi-functional zinc catalysts based on robust and easy-to-handle N-chelating ligands for the synthesis of cyclic carbonates from epoxides and CO2 under mild conditions
Rongchang Luo, Xiantai Zhou, Wuying Zhang, Zhongxiu Liang, Jun Jiang, Hongbing Ji
DOI: 10.1039/C4GC00671B
Structuration of ionic liquids in a poly(butylene-adipate-co-terephthalate) matrix: its influence on the water vapour permeability and mechanical properties
Valeria Bugatti, Bluma Guenther Soares
DOI: 10.1039/C4GC00969J
You might also like
How should 2-Methylbenzene-1,4-diamine dihydrochloride (CAS: 615-45-2) be stored?
2-Methylbenzene-1,4-diamine dihydrochloride (CAS: 615-45-2) should be stored in ...
Is (1S,4S)-2,5-Diazabicyclo[2.2.1]heptane dihydrobromide (CAS: 132747-20-7) safe?
(1S,4S)-2,5-Diazabicyclo[2.2.1]heptane dihydrobromide is generally considered sa...
What industries use (6-Chloropyridazin-3-YL)methanamine (CAS: 871826-15-2)?
(6-Chloropyridazin-3-YL)methanamine finds applications in the pharmaceutical ind...
What are the main uses of 2-Fluoro-3-methylphenol (CAS: 77772-72-6)?
2-Fluoro-3-methylphenol is primarily used in the synthesis of pharmaceuticals, p...
What precautions should be taken when handling 3-Methoxy-4-nitrobenzonitrile (CAS: 177476-75-4)?
When handling 3-Methoxy-4-nitrobenzonitrile, it is important to wear appropriate...
What precautions should be taken when handling 1,3-Oxazolo[4,5-b]pyridine-2(3H)-thione (CAS: 211949-57-4)?
When handling 1,3-Oxazolo[4,5-b]pyridine-2(3H)-thione (CAS: 211949-57-4), it is ...
What regulatory guidelines apply to 4-Ethynylbenzamide (CAS: 90347-86-7)?
4-Ethynylbenzamide (CAS: 90347-86-7) falls under various regulatory guidelines i...
What are the main uses of 3-(2-Ethylphenyl)-2-thioxo-4-imidazolidinone (CAS: 186822-57-1)?
3-(2-Ethylphenyl)-2-thioxo-4-imidazolidinone is primarily used as an intermediat...
What is (2-Fluoro-6-methoxyphenyl)acetic acid (CAS: 500912-19-6)?
(2-Fluoro-6-methoxyphenyl)acetic acid, also known as 4-fluoro-3-methoxybenzoic a...
What is the market or research trend for 2-[4-(Hydroxymethyl)phenoxy]ethanol (CAS: 102196-18-9)?
Market trends for 2-[4-(Hydroxymethyl)phenoxy]ethanol (CAS: 102196-18-9) indicat...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.










![1-Benzyl-1,7-diazaspiro[4.4]nonane dihydrochloride structure 1-Benzyl-1,7-diazaspiro[4.4]nonane dihydrochloride structure](https://static.chemtradehub.com/structs/115/1159822-71-5-0320.webp)
![trans-2-{[(Tert-butoxy)carbonyl]amino}cyclobutane-1-carboxylic acid structure trans-2-{[(Tert-butoxy)carbonyl]amino}cyclobutane-1-carboxylic acid structure](https://static.chemtradehub.com/structs/951/951173-25-4-27cd.webp)


