An alternative route for the synthesis of hydroxylated pillar[5]arene-based amphiphiles
Literature Information
Talal F. Al-Azemi, Mickey Vinodh, Fatemeh H. Alipour, Abdirahman A. Mohamod
Conformational mobilities of the units and host–guest complexation with n-octyltrimethylammonium hexafluorophosphate of the synthesized perbenzylated pillar[5]arenes were studied. The formed complex was confirmed by proton nuclear magnetic resonance spectroscopy and mass spectral analysis. Hydroxylated pillar[5]arene-based amphiphiles were synthesized by a co-cyclization strategy followed by catalytic hydrogenation. This approach unlocks the synthesis and the design of a wide range of structural manipulations to these amphiphilic pillararenes.
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Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.




