trans-4-(4-Morpholinyl)cyclohexanol hydrochloride (1:1)
CAS Number:
1588441-09-1
Molecular Formula:
C10H20ClNO2
Oligomer based real-time detection of microorganisms producing nuclease enzymes
Literature Information
Publication Date
2018-12-20
DOI
10.1039/C8AN02129E
Impact Factor
4.616
Authors
Sema Akyürek, Simay Gündüz, Muslum Akgoz
View Original
Abstract
In this study, we provide a method using fluorescently labeled oligonucleotides for the diagnosis of microorganisms producing nucleases in real time, while growing them in culture media. The detection of such microorganisms was possible in a short period of time, as short as 10 minutes up to a maximum of 8 hours, depending on the bacterial density. We also showed the suitability of this new method for determination of minimum inhibitory concentration (MIC) in culture media in a very short period of time, compared to conventional methods. We believe that it can make a significant contribution to gain new insights for analysis of complex materials such as clinical samples, food samples and environmental samples.
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Source Journal
Analyst
CiteScore:
7.8
Self-citation Rate:
5.6%
Articles per Year:
653
Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
Recommended Compounds
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2-Methyl-2-propanyl 1,6-diazaspiro[3.4]octane-6-carboxylate
CAS Number:
1158749-79-1
Molecular Formula:
C11H20N2O2
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4-{1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropyl}morpholine
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Molecular Formula:
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