Iodine(iii)-mediated intramolecular sulfeno- and selenofunctionalization of β,γ-unsaturated tosyl hydrazones and oximes

Literature Information

Publication Date 2017-12-18
DOI 10.1039/C7OB02892J
Impact Factor 3.876
Authors

Jing-Miao Yu, Chun Cai


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Abstract

A cascade radical cyclization/sulfenylation or selenylation of β,γ-unsaturated hydrazones and oximes was realized under mild conditions with phenyliodine(III) diacetate (PIDA) as the sole oxidant, leading to the construction of diversely functionalized heteroatom-containing pyrazoline and isoxazoline derivatives. This metal-free radical process is suggested to encompass a sequential C–N/O and C–S/Se bond fomation.

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Organic & Biomolecular Chemistry
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