Dynamic evolution of a vesicle formed by comb-like block copolymer-tethered nanoparticles: a dissipative particle dynamics simulation study

Literature Information

Publication Date 2017-09-15
DOI 10.1039/C7CP05196D
Impact Factor 3.676
Authors

Ying-Tao Liu, Yan-Rong Li, Xin Wang


View Original

Abstract

Vesicles are well-sealed capsules that can store or transport substances. Their dynamic evolution mechanisms are important to fulfill specific functions. In the present study, dissipative particle dynamics (DPD) simulation was employed to study the formation, fusion, and fission pathways of vesicles. Our results show that comb-like block copolymer-tethered nanoparticles can self-assemble into stable vesicles, which may be a good candidate for drug entrapment and controlled release of drug. The spontaneous fusion of this type of vesicles has been studied, whose mechanism is different from that of the vesicles formed from comb-like block copolymers. However, the fission mechanisms of the two types of vesicles are similar. To summarize, the introduction of nanoparticles alters the fusion mechanism, but causes no difference in the fission pathway of vesicles. The reason may be attributed to the nature of nanoparticles. The fusion and fission processes always experience the congregation of nanoparticles. The large and rigid nanoparticles inevitably result in changes of surface tension of the vesicle that is a key factor influencing the membrane dynamics.

Related Literature

Crystalline oligopyrene nanowires with multicolored emission

Liangti Qu, Gaoquan Shi

2004-11-03 Communication

DOI: 10.1039/B412638F

Facile resolution of constrained geometry indenyl-phenoxide ligation

Luke E. Turner, Matthew G. Thorn, Phillip E. Fanwick, Ian P. Rothwell

2003-03-28 Communication

DOI: 10.1039/B212724E

The role of isomorphism in synthetic analysis. Pruning the search tree by finding disjoint isomorphic substructures

Steven H. Bertz, Toby J. Sommer

2003-03-25 Communication

DOI: 10.1039/B300935A

Carene terpenoids by gold-catalyzed cycloisomerization reactions

Alois Fürstner, Peter Hannen

2004-10-06 Communication

DOI: 10.1039/B412354A

Zeolite coated ATR crystals for new applications in FTIR-ATRspectroscopy

Zheng Wang, Margareta L. Larsson, Mattias Grahn, Allan Holmgren, Jonas Hedlund

2004-10-25 Communication

DOI: 10.1039/B410314A

Zeolitenanoparticles with immobilized metal ions: isolation and MALDI-TOF-MS/MS identification of phosphopeptides

Yahong Zhang, Xijuan Yu, Xiaoyan Wang, Wei Shan, Pengyuan Yang, Yi Tang

2004-10-25 Communication

DOI: 10.1039/B411336E

Synthesis and characterization of a benzene-centered, phthalocyanine hexamer

Giovanni Bottari, Tomás Torres

2004-10-14 Communication

DOI: 10.1039/B411960F

Synthesis of C-arylglycosides via Ru(ii)-catalyzed [2 + 2 + 2] cycloaddition

Yoshihiko Yamamoto, Tomoaki Saigoku, Takashige Ohgai, Hisao Nishiyama, Kenji Itoh

2004-10-07 Communication

DOI: 10.1039/B411442F

A new route to fullerene substituted phenylalanine derivatives

Jianzhong Yang, Andrew R. Barron

2004-10-25 Communication

DOI: 10.1039/B411118D

Construction of a protein array on amyloid-like fibrils using co-assembly of designed peptides

Hiroyuki Kodama, Sachiko Matsumura, Taro Yamashita, Hisakazu Mihara

2004-10-25 Communication

DOI: 10.1039/B409641J

You might also like

Compound Q&A

What industries use (1R,3S)-1,3-Cyclopentanediol (CAS: 16326-97-9)?

(1R,3S)-1,3-Cyclopentanediol finds applications in various industries. In the ph...

16326-97-9(1R,3S)-1,3-Cyclopen...
Compound Q&A

What precautions should be taken when handling N'-[4-(Dimethylamino)phenyl]-N,N-dimethyl-1,4-benzenediamine (CAS: 637-31-0)?

When handling N'-[4-(Dimethylamino)phenyl]-N,N-dimethyl-1,4-benzenediamine, it i...

637-31-0N'-[4-(Dimethylamino...
Compound Q&A

Are there alternatives to 5-(2,4-Difluorophenyl)-2-methoxypyrimidine (CAS: 1352318-16-1) in synthesis?

There are several alternatives to 5-(2,4-Difluorophenyl)-2-methoxypyrimidine in ...

1352318-16-15-(2,4-Difluoropheny...
Compound Q&A

What regulatory guidelines apply to 1-(3-Methoxyphenoxy)propan-2-ol (CAS: 382141-68-6)?

1-(3-Methoxyphenoxy)propan-2-ol (CAS: 382141-68-6) must comply with the Globally...

382141-68-61-(3-Methoxyphenoxy)...
Compound Q&A

Is Tetrodotoxin Citrate (CAS: 18660-81-6) safe?

Tetrodotoxin Citrate is extremely dangerous and should be handled with extreme c...

18660-81-6Tetrodotoxin Citrate
Compound Q&A

What are the main uses of 2-Methyl-2-propanyl [(1R,3S)-3-hydroxycyclopentyl]carbamate (CAS: 225641-84-9)?

2-Methyl-2-propanyl [(1R,3S)-3-hydroxycyclopentyl]carbamate (CAS: 225641-84-9) i...

225641-84-92-Methyl-2-propanyl ...
Compound Q&A

How should waste containing 4-(2-Hydroxyhexafluoroisopropyl)Benzoic Acid (CAS: 16261-80-6) be handled?

Waste containing 4-(2-Hydroxyhexafluoroisopropyl)Benzoic Acid (CAS: 16261-80-6) ...

16261-80-64-(2-Hydroxyhexafluo...
Compound Q&A

How is 2-Methyl-2-proanyl {(2S)-1-[(benzyloxy)amino]-3-hydroxy-3-methyl-1-oxo-2-butanyl}carbamate (CAS: 102507-19-7) typically synthesized?

2-Methyl-2-proanyl {(2S)-1-[(benzyloxy)amino]-3-hydroxy-3-methyl-1-oxo-2-butanyl...

102507-19-72-Methyl-2-propanyl ...
Compound Q&A

What is Benzeneethanamine, α-ethyl-, hydrochloride (1:1) (CAS: 20735-15-3)?

Benzeneethanamine, α-ethyl-, hydrochloride (1:1) is an organic compound with the...

20735-15-3Benzeneethanamine, α...
Compound Q&A

Are there alternatives to 3-{(E)-[4-(Dimethylamino)phenyl]diazenyl}benzoic acid (CAS: 20691-84-3) in synthesis?

In the synthesis of compounds similar to 3-{(E)-[4-(Dimethylamino)phenyl]diazeny...

20691-84-33-{(E)-[4-(Dimethyla...

Source Journal

Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics
CiteScore: 5.5
Self-citation Rate: 10.3%
Articles per Year: 3036

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.