Copper nitrate-mediated chemo- and regioselective annulation from two different alkynes: a direct route to isoxazoles

Literature Information

Publication Date 2016-12-20
DOI 10.1039/C6QO00704J
Impact Factor 5.281
Authors

Yingying Li, Mingchun Gao, Bingxin Liu


View Original

Abstract

An efficient copper nitrate-mediated annulation reaction was developed for the direct synthesis of pharmacologically interesting polysubstituted isoxazoles in good to excellent yields from two different alkynes with high chemo- and regioselectivities by syringe pump infusion.

Related Literature

Electronic structure calculations and nonadiabatic dynamics simulations of excited-state relaxation of Pigment Yellow 101

Meng Che, Yuan-Jun Gao, Yan Zhang, Shu-Hua Xia, Ganglong Cui

2018-02-05 Paper

DOI: 10.1039/C7CP07692D

Sub-μL measurements of the thermal conductivity and heat capacity of liquids

C. López-Bueno, D. Bugallo, V. Leborán, F. Rivadulla

2018-02-08 Paper

DOI: 10.1039/C8CP00165K

Isomer-specific detection in the UV photodissociation of the propargyl radical by chirped-pulse mm-wave spectroscopy in a pulsed quasi-uniform flow

Bernadette M. Broderick, Nicolas Suas-David, Nureshan Dias, Arthur G. Suits

2017-11-13 Paper

DOI: 10.1039/C7CP06211G

Theoretical investigation of the infrared spectrum of small polyynes

Kirstin D. Doney, Dongfeng Zhao, John F. Stanton, Harold Linnartz

2017-11-03 Paper

DOI: 10.1039/C7CP06131E

Sumanene: an efficient π-bowl for dihydrogen storage

2018-02-01 Paper

DOI: 10.1039/C7CP07000D

Ammonolysis of ketene as a potential source of acetamide in the troposphere: a quantum chemical investigation

Saptarshi Sarkar, Subhasish Mallick, Pradeep Kumar, Biman Bandyopadhyay

2018-04-25 Paper

DOI: 10.1039/C8CP01650J

Open flow non-enzymatic template catalysis and replication

Larwsk H. Gonçalves da Silva, David Hochberg

2018-05-11 Paper

DOI: 10.1039/C8CP01828F

Transition of surface phase of cobalt oxide during CO oxidation

Yu Tang, Jian Dou, Christopher M. Andolina, Yuting Li, Hongbin Ma, Stephen D. House, Xiaoyan Zhang, Judith Yang, Franklin (Feng) Tao

2018-01-02 Paper

DOI: 10.1039/C7CP07407G

You might also like

Compound Q&A

What precautions should be taken when handling 4-Methyl-6-(trifluoromethyl)quinoline (CAS: 40716-16-3)?

When handling 4-Methyl-6-(trifluoromethyl)quinoline (CAS: 40716-16-3), safety go...

40716-16-34-Methyl-6-(trifluor...
Compound Q&A

What is 4-(3,5-Difluorophenyl)aniline (CAS: 405058-00-6)?

4-(3,5-Difluorophenyl)aniline is an aromatic organic compound with the CAS numbe...

405058-00-64-(3,5-Difluoropheny...
Compound Q&A

How is 5-{[4-(Trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylic acid (CAS: 338982-07-3) typically synthesized?

5-{[4-(Trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylic acid can ...

338982-07-35-{[4-(Trifluorometh...
Compound Q&A

What is the market or research trend for 4-Benzylaniline hydrochloride (CAS: 6317-57-3)?

The market for 4-Benzylaniline hydrochloride (CAS: 6317-57-3) is steadily growin...

6317-57-34-Benzylaniline hydr...
Compound Q&A

Is [3-(Diethylsulfamoyl)phenyl]boronic acid (CAS: 871329-58-7) safe?

[3-(Diethylsulfamoyl)phenyl]boronic acid is generally considered safe when handl...

871329-58-7[3-(Diethylsulfamoyl...
Compound Q&A

What are the main uses of 3-Bromo-2,5-dimethoxyaniline (CAS: 115929-62-9)?

3-Bromo-2,5-dimethoxyaniline is mainly used in the pharmaceutical and chemical i...

115929-62-93-Bromo-2,5-dimethox...
Compound Q&A

What regulatory guidelines apply to N-Methyl-1-(5-methyl-1H-indol-3-yl)methanamine (CAS: 915922-67-7)?

N-Methyl-1-(5-methyl-1H-indol-3-yl)methanamine (CAS: 915922-67-7) is subject to ...

915922-67-7N-Methyl-1-(5-methyl...
Compound Q&A

What industries use Carbamic acid, N-[(5S)-5,6-diamino-6-oxohexyl]-, 1,1-dimethylethyl ester (CAS: 24828-96-4)?

This compound is primarily used in the pharmaceutical industry for the synthesis...

24828-96-4Carbamic acid, N-[(5...
Compound Q&A

How should 2-Methyl-2-propanyl [(1S,3R)-3-aminocyclohexyl]carbamate (CAS: 1298101-47-9) be stored?

2-Methyl-2-propanyl [(1S,3R)-3-aminocyclohexyl]carbamate (CAS: 1298101-47-9) sho...

1298101-47-92-Methyl-2-propanyl ...
Compound Q&A

What industries use Ethyl 2-bromo-4,4,4-trifluorobutanoate (CAS: 367-33-9)?

Ethyl 2-bromo-4,4,4-trifluorobutanoate (CAS: 367-33-9) is utilized in the pharma...

367-33-9Ethyl 2-bromo-4,4,4-...

Source Journal

Organic Chemistry Frontiers

Organic Chemistry Frontiers
CiteScore: 7.8
Self-citation Rate: 8.7%
Articles per Year: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.