2-(5-Bromo-2-methyl-2H-indazol-3-yl)-2-propanol
CAS Number:
1823787-20-7
Molecular Formula:
C11H13BrN2O
Transition-metal-free electrophilic trifluoromethylthiolation with sodium trifluoromethanesulfinate at room temperature
Literature Information
Publication Date
2016-11-29
DOI
10.1039/C6QO00622A
Impact Factor
5.281
Authors
Mei-jie Bu, Guo-ping Lu
View Original
Abstract
A transition-metal-free direct trifluoromethylthiolation of indole derivatives under mild conditions has been developed. Commercially available sodium trifluoromethanesulfinate (CF3SO2Na) acts as the trifluoromethylthiolating reagent, which is cheap, stable and easy to handle. The substrate scope of this protocol could also be expanded to pyrroles and enamines.
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Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
5-(6-Methoxy-1-benzofuran-2-yl)-2-(3-methyl-2-buten-1-yl)-1,3-benzenediol
CAS Number:
1017277-40-5
Molecular Formula:
C20H20O4
![3-[7-Amino-3-(3-pyridinyl)pyrazolo[1,5-a]pyrimidin-6-yl]phenol structure](https://static.chemtradehub.com/structs/861/861249-77-6-025b.webp "3-[7-Amino-3-(3-pyridinyl)pyrazolo[1,5-a]pyrimidin-6-yl]phenol structure")
3-[7-Amino-3-(3-pyridinyl)pyrazolo[1,5-a]pyrimidin-6-yl]phenol
CAS Number:
861249-77-6
Molecular Formula:
C17H13N5O
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