3-(Methylamino)-1-phenyl-1-propanone hydrochloride (1:1)
CAS Number:
2538-50-3
Molecular Formula:
C10H14ClNO
Investigation on the controlled synthesis and post-modification of poly-[(N-2-hydroxyethyl)-aspartamide]-based polymers
Literature Information
Publication Date
2017-02-07
DOI
10.1039/C6PY02230H
Impact Factor
5.582
Authors
Shixian Lv, Yuchen Wu, Jingqi Dang, Zhaohui Tang, Ziyuan Song, Sheng Ma, Xiao Wang, Xuesi Chen, Lichen Yin
View Original
Abstract
The production of poly-[(N-2-hydroxyethyl)-aspartamide] (PHEA)-based materials is hampered by the unsatisfactory synthesis and low reactivity in terms of post-modification. Herein, we report the controlled synthesis of PHEA-based polymers, unraveled the hydrogen bonding in PHEA, developed effective approaches to enhance the reactivity of PHEA by improving the temperature, and further demonstrated the desired aqueous solubility as well as the lyophilization stability of PHEA-based amphiphiles. This study will provide insights into the design of useful and functionalized polypeptide-based biomaterials.
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Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
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1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]-3,5-pyrazolidinedione
CAS Number:
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Molecular Formula:
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