Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

Literature Information

Publication Date 2016-09-23
DOI 10.1039/C6PY01480A
Impact Factor 5.582
Authors

Bo Wang, Thomas Blin, Aleksandr Käkinen, Xinwei Ge, Emily H. Pilkington, John F. Quinn, Michael R. Whittaker, Pu Chun Ke, Feng Ding


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Abstract

To provide a molecular insight for guiding polymer coating in surface science and nanotechnology, here we examined the structures of brushed polyethylene glycol(bPEG)- and phosphorylcholine(bPC)-grafted iron oxide nanoparticles and analyzed their protein avoiding properties. We show bPC as an advantageous biomimetic alternative to PEG in rendering stealth nanostructures.

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Polymer Chemistry

Polymer Chemistry
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