Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding
Literature Information
Bo Wang, Thomas Blin, Aleksandr Käkinen, Xinwei Ge, Emily H. Pilkington, John F. Quinn, Michael R. Whittaker, Pu Chun Ke, Feng Ding
To provide a molecular insight for guiding polymer coating in surface science and nanotechnology, here we examined the structures of brushed polyethylene glycol(bPEG)- and phosphorylcholine(bPC)-grafted iron oxide nanoparticles and analyzed their protein avoiding properties. We show bPC as an advantageous biomimetic alternative to PEG in rendering stealth nanostructures.
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