Graphene oxide–peptide nanoassembly as a general approach for monitoring the activity of histone deacetylases

Literature Information

Publication Date 2016-05-12
DOI 10.1039/C6AN00902F
Impact Factor 4.616
Authors

Ping Liang, Qing Li, Zhan Wu, Jian-Hui Jiang, Ru-Qin Yu


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Abstract

A novel fluorescent sensor using graphene oxide (GO)–peptide nanoassembly is developed for histone deacetylases (HDACs) based on deacetylation mediated cleavage of substrate peptides, which provides a simple, cost-effective platform for monitoring the activity of HDACs.

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