Graphene oxide-based electrochemical label-free detection of glycoproteins down to aM level using a lectin biosensor
Literature Information
Publication Date
2016-05-31
DOI
10.1039/C6AN00793G
Impact Factor
4.616
Authors
L. Klukova, J. Filip, S. Belicky, A. Vikartovska, J. Tkac
View Original
Abstract
A label-free ultrasensitive impedimetric biosensor with lectin immobilised on graphene oxide (GO) for the detection of glycoproteins from 1 aM is shown here. This is the first time a functional lectin biosensor with lectin directly immobilised on a graphene-based interface without any polymer modifier has been described. The study also shows that hydrophilic oxidative debris present on GO has a beneficial effect on the sensitivity of (8.46 ± 0.20)% per decade for the lectin biosensor compared to the sensitivity of (4.52 ± 0.23)% per decade for the lectin biosensor built up from GO with the oxidative debris washed out.
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Analyst
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Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
Recommended Compounds
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800381-60-6
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C14H16BrF3
Ethyl 2,4-bis(trifluoromethyl)-5-pyrimidinecarboxylate
CAS Number:
188781-15-9
Molecular Formula:
C9H6F6N2O2
![8-Bromo-6-fluoro[1,2,4]triazolo[1,5-a]pyridin-2-amine structure](https://static.chemtradehub.com/structs/125/1257705-51-3-9f4a.webp "8-Bromo-6-fluoro[1,2,4]triazolo[1,5-a]pyridin-2-amine structure")
8-Bromo-6-fluoro[1,2,4]triazolo[1,5-a]pyridin-2-amine
CAS Number:
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Molecular Formula:
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