Gold-catalyzed tandem synthesis of bioactive spiro-dipyrroloquinolines and its application in the one-step synthesis of incargranine B aglycone and seneciobipyrrolidine (I)
Literature Information
Publication Date
2016-01-06
DOI
10.1039/C5QO00354G
Impact Factor
5.281
Authors
Can-Liang Ma, Xiao-Hua Li, Xiao-Long Yu, Xiao-Long Zhu, Yong-Zhou Hu, Xiao-Wu Dong, Bin Tan, Xin-Yuan Liu
View Original
Abstract
The Au-catalyzed tandem process of aminoalkynes was explored, providing simple and efficient access to richly functionalized dipyrroloquinoline frameworks with good to excellent yields. The reaction exhibits great efficiency and high atom economy in multiple-bond formation for constructing bioactive azaspiro polycyclic molecules with densely multiple stereogenic centers including quaternary carbons, and shows a broad substrate scope and synthetically important functional group tolerance, which have been illustrated in the first one-step synthesis of incargranine B aglycone and seneciobipyrrolidine (I).
Recommended Journals
Russian Journal of Coordination Chemistry
Russian Journal of Applied Chemistry
Russian Chemical Bulletin
Journal of Peptide Science
Current Opinion in Solid State & Materials Science
Organic Process Research & Development
Russian Journal of Bioorganic Chemistry
Current Opinion in Colloid & Interface Science
Saudi Pharmaceutical Journal
Acta Materialia
Related Literature
Macromolecular covalently cross-linked quaternary ammonium poly(ether ether ketone) with polybenzimidazole for anhydrous high temperature proton exchange membranes
Na Zhang, Chengji Zhao, Wenjia Ma, Shuang Wang, Baolong Wang, Gang Zhang, Xuefeng Li, Hui Na
2014-04-14
Paper
DOI: 10.1039/C4PY00234B
Supramolecular flower micelle formation of polyrotaxane-containing triblock copolymers prepared from macro-chain transfer agents bearing molecular hooks
Atsushi Tamura, Hajime Tanaka, Nobuhiko Yui
2014-05-16
Paper
DOI: 10.1039/C4PY00379A
Synthesis and characterization of isosorbide-based polyphosphonates as biobased flame-retardants
Timothy C. Mauldin, Jeffrey W. Gilman, John R. Shields, Dylan J. Boday
2014-06-02
Paper
DOI: 10.1039/C4PY00591K
Dimanganese decacarbonyl/2-cyanoprop-2-yl-1-dithionaphthalate: toward sunlight induced RAFT polymerization of MMA
Xuelang Miao, Jiajia Li, Zhengbiao Zhang, Zhenping Cheng, Wei Zhang, Jian Zhu, Xiulin Zhu
2014-04-23
Paper
DOI: 10.1039/C4PY00509K
Controlling micro-phase separation in semi-crystalline/amorphous conjugated block copolymers
Lianshan Li, Zhiyuan Tian, Zhiyong Tang
2014-05-21
Communication
DOI: 10.1039/C4PY00498A
Novel hydroxyl-containing reduction-responsive pseudo-poly(aminoacid) via click polymerization as an efficient drug carrier
Zhigang Xie, Xuesi Chen, Xiabin Jing, Yubin Huang
2014-03-27
Paper
DOI: 10.1039/C4PY00227J
Nano-building block based-hybrid organic–inorganic copolymers with self-healing properties
A. Guinault, S. Delalande
2014-04-03
Paper
DOI: 10.1039/C4PY00172A
In vitro and in vivo application of hydroxypropyl-β-cyclodextrin-grafted polyethyleneimine used as a transdermal penetration enhancer
Ke Wang, Yan Yan, Guilan Zhao, Wei Xu, Kai Dong, Cuiyu You, Lu Zhang, Jianfeng Xing
2014-03-14
Paper
DOI: 10.1039/C4PY00286E
You might also like
Compound Q&A
What is Ethyl 3-cyclohexylpropanoate (CAS: 10094-36-7)?
Ethyl 3-cyclohexylpropanoate is a clear, colorless to light yellow liquid with a...
10094-36-7Ethyl 3-cyclohexylpr...
Compound Q&A
How should waste containing 2-(Hydroxymethyl)-5-(methoxycarbonyl)-6-methyl-4-(2-nitrophenyl)nicotinic acid (CAS: 34783-31-8) be handled?
Waste containing 2-(Hydroxymethyl)-5-(methoxycarbonyl)-6-methyl-4-(2-nitrophenyl...
34783-31-82-(Hydroxymethyl)-5-...
Compound Q&A
How should waste containing 2,4,6-Tris(pentafluoroethyl)-1,3,5-triazine (CAS: 858-46-8) be handled?
Waste containing 2,4,6-Tris(pentafluoroethyl)-1,3,5-triazine (CAS: 858-46-8) sho...
858-46-82,4,6-Tris(pentafluo...
Compound Q&A
What precautions should be taken when handling Chloroac-nle-oh (CAS: 56787-36-1)?
When handling Chloroac-nle-oh (CAS: 56787-36-1), it is essential to wear appropr...
56787-36-1Chloroac-nle-oh
Compound Q&A
What industries use Ethyl 6-phenylimidazo[2,1-b][1,3]thiazole-3-carboxylate (CAS: 752244-05-6)?
Ethyl 6-phenylimidazo[2,1-b][1,3]thiazole-3-carboxylate is primarily used in the...
752244-05-6Ethyl 6-phenylimidaz...
Compound Q&A
Are there alternatives to alpha-(2-Bromophenyl)benzylamine (CAS: 55095-15-3) in synthesis?
Alternatives to alpha-(2-Bromophenyl)benzylamine (CAS: 55095-15-3) in synthesis ...
55095-15-3alpha-(2-Bromophenyl...
Compound Q&A
How should waste containing 2-Chloro-5-methoxypyridine (CAS: 139585-48-1) be handled?
Waste containing 2-Chloro-5-methoxypyridine (CAS: 139585-48-1) should be managed...
139585-48-12-Chloro-5-methoxypy...
Compound Q&A
What industries use 1-(4-Methoxyphenyl)-2,5-dimethyl-1H-pyrrole (CAS: 5044-27-9)?
1-(4-Methoxyphenyl)-2,5-dimethyl-1H-pyrrole (CAS: 5044-27-9) is used in various ...
5044-27-91-(4-Methoxyphenyl)-...
Compound Q&A
Are there alternatives to 3-Bromo-5-(N-Boc)aminomethylisoxazole (CAS: 903131-45-3) in synthesis?
There are alternative reagents and compounds that can be used in the synthesis o...
903131-45-33-Bromo-5-(N-Boc)ami...
Compound Q&A
What is Tungsten(IV) oxide (CAS: 12036-22-5)?
Tungsten(IV) oxide, also known as tungsten dioxide, is a chemical compound with ...
12036-22-5Tungsten(IV) oxide
Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.