1-(3-Fluorophenyl)-1H-1,2,4-triazole-3-carboxylic acid
CAS Number:
1292369-51-7
Molecular Formula:
C9H6FN3O2
Copper-mediated C(sp3)–H amination in a multiple C–N bond-forming strategy for the synthesis of N-heterocycles
Literature Information
Publication Date
2015-11-20
DOI
10.1039/C5QO00313J
Impact Factor
5.281
Authors
Zeqiang Xie, Jiangling Peng, Qiang Zhu
View Original
Abstract
An efficient construction of imidazo[1,5-a]pyridines, through a three-component reaction involving benzyl substituted pyridines, aldehydes, and TMSN3, has been developed. Three C–N bonds were formed in one pot. Copper-promoted amination of the benzylic C(sp3)–H bond is a key step of this multiple C–N bond-forming sequence.
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Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
![tert-Butyl 6-chloro-4-oxospiro[chroman-2,4'-piperidine]-1'-carboxylate structure](https://static.chemtradehub.com/structs/101/1011482-37-3-88a5.webp "tert-Butyl 6-chloro-4-oxospiro[chroman-2,4'-piperidine]-1'-carboxylate structure")
tert-Butyl 6-chloro-4-oxospiro[chroman-2,4'-piperidine]-1'-carboxylate
CAS Number:
1011482-37-3
Molecular Formula:
C18H22ClNO4
5,5',5''-(((2,4,6-Trimethylbenzene-1,3,5-triyl)tris(methylene))tris(oxy))triisophthalic acid
CAS Number:
1159974-70-5
Molecular Formula:
C36H30O15
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