Copper-catalyzed domino synthesis of benzo[b]thiophene/imidazo[1,2-a]pyridines by sequential Ullmann-type coupling and intramolecular C(sp2)–H thiolation

Literature Information

Publication Date 2015-11-17
DOI 10.1039/C5QO00311C
Impact Factor 5.281
Authors

Kelu Yan, Daoshan Yang, Wei Wei, Shenglei Lu, Guoqing Li, Caixia Zhao, Qingyun Zhang, Hua Wang


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Abstract

The copper-catalyzed double C–S bond formation via Ullmann-type S-arylation and C–H thiolation using K2S as a sulfur source is described. This novel one-step sulfur-incorporation method provides a straightforward avenue to benzo[b]thiophene and imidazo[1,2-a]pyridine frameworks.

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DOI: 10.1039/C4PY90042A

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Source Journal

Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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