Reactive oxygen species (ROS)-responsive tellurium-containing hyperbranched polymer

Literature Information

Publication Date 2015-02-10
DOI 10.1039/C5PY00050E
Impact Factor 5.582
Authors

Ruochen Fang, Huaping Xu, Wei Cao, Liulin Yang, Xi Zhang


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Abstract

Materials responsive to reactive oxygen species (ROS) at a physiological level are of great significance in diagnostic and therapeutic applications. We have synthesized a water-soluble tellurium-containing hyperbranched polymer and demonstrated that it forms a kind of ROS-responsive aggregate. In aqueous environment, the polymer aggregates can swell under biologically relevant concentration of H2O2, which could be expected to find applications in fields such as elimination of excess ROS.

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Polymer Chemistry

Polymer Chemistry
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Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

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