Ultrafast deactivation of bilirubin: dark intermediates and two-photon isomerization
Literature Information
Carlos Carreira-Blanco, Patrick Singer, Rolf Diller, J. Luis Pérez Lustres
Bilirubin is a neurotoxic product responsible for neonatal jaundice, which is generally treated by phototherapy. The photoreaction involves ultrafast internal conversion via an elusive intermediate and Z–E isomerization with minor yield (less than 3% in solution). The structure of the intermediate remains unclear. Here, the combination of UV-vis and mid-IR ultrafast transient absorption spectroscopy reports a comprehensive picture of the mechanism and provides essential structural information about the intermediate species. Thus, spectral dynamics during the earliest ps unveils a wavepacket travelling from the Franck–Condon region to the crossing point with a dark state. The latter shows a tighter molecular skeleton than the ground state and decays with 15 ps time constant. Remarkably, the relative contribution of a non-decaying component increases linearly with pump energy, suggesting that Z–E isomerization could also be triggered by two-photon excitation. Implications for the photochemistry of protein-bound open tetrapyrroles are discussed.
Related Literature
[1]Benzothieno[3,2-b][1]benzothiophene-based dyes: effect of the ancillary moiety on mechanochromism and aggregation-induced emission
Rajamouli Boddula
DOI: 10.1039/D2CP01934E
The ligand field in low-crystallinity metal–organic frameworks investigated by soft X-ray core-level absorption spectroscopy
Kohei Yamagami, Hirona Yamagishi, Hiroyuki Setoyama, Arata Tanaka, Ryo Ohtani, Masaaki Ohba
DOI: 10.1039/D2CP01415G
Molecular hydrogen isotope separation by a graphdiyne membrane: a quantum-mechanical study
José Campos-Martínez, Massimiliano Bartolomei, Fernando Pirani, Marta I. Hernández
DOI: 10.1039/D2CP01044E
Insight on noncovalent interactions and orbital constructs in low-dimensional antimony halide perovskites
Aaron D. Nicholas, Leah C. Garman, Nicolina Albano, Christopher L. Cahill
DOI: 10.1039/D2CP01996E
Breakthrough pressure of oil displacement by water through the ultra-narrow kerogen pore throat from the Young–Laplace equation and molecular dynamic simulations
Yinuo Zhao, Wenhui Li, Zhehui Jin
DOI: 10.1039/D2CP01643E
Can domain-based local pair natural orbitals approaches accurately predict phosphorescence energies?
Giovanna Bruno, Bernardo de Souza, Frank Neese
DOI: 10.1039/D2CP01623K
Heat managing organic materials: phase change materials with high thermal conductivity and shape stability
Hyeyoon Ko, Dong-Gue Kang, Minwoo Rim, Jahyeon Koo, Seok-In Lim, Eunji Jang, Dongmin Yu, Myong-Jae Yoo, Namil Kim, Kwang-Un Jeong
DOI: 10.1039/D1PY01318A
High-performance Ruddlesden–Popper two-dimensional perovskite solar cells via solution processed inorganic charge transport layers
Zhihai Liu, Lei Wang, Xiaoyin Xie, Chongyang Xu, Jianfeng Tang, Wei Li
DOI: 10.1039/D2CP02033E
Chromone–methanol clusters in the electronic ground and lowest triplet state: a delicate interplay of non-covalent interactions
Pol Boden, Patrick H. Strebert, Marcel Meta, Christoph Riehn, Markus Gerhards
DOI: 10.1039/D2CP01341J
Donors, acceptors, and a bit of aromatics: electronic interactions of molecular adsorbates on hBN and MoS2 monolayers
Jannis Krumland, Marcella Iannuzzi
DOI: 10.1039/D2CP01502A
You might also like
What precautions should be taken when handling 2-Methyl-2-propanyl 5-amino-2-thiophenecarboxylate (CAS: 1498311-57-1)?
When handling 2-Methyl-2-propanyl 5-amino-2-thiophenecarboxylate (CAS: 1498311-5...
What are the physical and chemical properties of 5-Bromo-1,2-dichloro-3-fluorobenzene (CAS: 1000572-93-9)?
5-Bromo-1,2-dichloro-3-fluorobenzene (CAS: 1000572-93-9) is a crystalline solid ...
How should (2R)-2-Amino-2-(4-bromophenyl)ethanol (CAS: 354153-64-3) be stored?
(2R)-2-Amino-2-(4-bromophenyl)ethanol (CAS: 354153-64-3) should be stored in a c...
What regulatory guidelines apply to Methyl 4-(aminomethyl)tetrahydro-2H-pyran-4-carboxylate hydrochloride (CAS: 362707-24-2)?
Methyl 4-(aminomethyl)tetrahydro-2H-pyran-4-carboxylate hydrochloride (CAS: 3627...
What are the main uses of 1,4-dimethyl-1H-pyrazole-5-sulfonyl chloride (CAS: 1174834-52-6)?
1,4-Dimethyl-1H-pyrazole-5-sulfonyl chloride is primarily used as an intermediat...
Is Dinaphtho[1,2-b:2',1'-d]furan (CAS: 239-69-0) safe?
Dinaphtho[1,2-b:2',1'-d]furan is generally safe when handled with appropriate pe...
What is the market or research trend for 7-Methyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione (CAS: 612-37-3)?
The market for 7-Methyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione (CAS: 612-37-3) i...
What are the physical and chemical properties of 2-(4-Chlorophenyl)malonaldehyde (CAS: 205676-17-1)?
2-(4-Chlorophenyl)malonaldehyde (CAS: 205676-17-1) is a colorless or light yello...
How is 2-Methylchrysene (CAS: 3351-32-4) typically synthesized?
2-Methylchrysene (CAS: 3351-32-4) is typically synthesized via the reaction of c...
Is N-(6-aminopyrimidin-4-yl)acetamide (CAS: 89533-23-3) safe?
N-(6-aminopyrimidin-4-yl)acetamide (CAS: 89533-23-3) is generally considered saf...
Source Journal
Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.











![1-{[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-thienyl]methyl}piperidine structure 1-{[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-thienyl]methyl}piperidine structure](https://static.chemtradehub.com/structs/121/1218790-44-3-baef.webp)

![L-Lysine,N6-[2-[[(1,1-dimethylethoxy)carbonyl]amino]benzoyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]- structure L-Lysine,N6-[2-[[(1,1-dimethylethoxy)carbonyl]amino]benzoyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]- structure](https://static.chemtradehub.com/structs/159/159322-59-5-c046.webp)
![2-[2-(2-Methoxyethoxy)ethoxy]-2-methylpropane structure 2-[2-(2-Methoxyethoxy)ethoxy]-2-methylpropane structure](https://static.chemtradehub.com/structs/527/52788-79-1-71c1.webp)