Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles

Literature Information

Publication Date 2015-06-04
DOI 10.1039/C5CP02387D
Impact Factor 3.676
Authors

Cristian C. Villa, N. Mariano Correa, Juana J. Silber, Fernando Moyano, R. Darío Falcone


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Abstract

In the present work, we study different physicochemical properties of the spontaneous unilamellar vesicles created by the catanionic ionic liquid-like surfactant benzyl-n-hexadecyldimethylammonium 1,4-bis-2-ethylhexylsulfosuccinate (AOT-BHD), using two different fluorescent probes: 6-propionyl-2-(dimethylaminonaphthalene), PRODAN and trans-4-[4-(dimethylamino)-styryl]-1-methylpyridinium iodide, HC. Steady-state and time resolved fluorescence emission spectroscopy allowed us to find the unique properties of the AOT-BHD bilayer in comparison with vesicles formed using the traditional phospholipid 1,2-di-oleoyl-sn-glycero-3-phosphatidylcholine, DOPC. From the emission results, we observed that the region of the bilayer close to the polar head of AOT-BHD is a powerful electron donor environment, even larger than DOPC. Additionally, the AOT-BHD bilayer offers a less polar and slightly more viscous zone than DOPC. Thus, this particular bilayer is able to produce large incorporation of ionic and nonionic molecules and is very promising to be used as a nanocarrier in pharmacological, cosmetic and food fields.

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Source Journal

Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics
CiteScore: 5.5
Self-citation Rate: 10.3%
Articles per Year: 3036

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.

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