A new type of biocompatible fluorescent probe AFN for fixed and live cell imaging of intracellular lipid droplets
Literature Information
Publication Date
2015-10-21
DOI
10.1039/C5AN01623A
Impact Factor
4.616
Authors
Ashutosh Sharma, Shahida Umar, Parmita Kar, Kavita Singh, Monika Sachdev
View Original
Abstract
We discovered a new class of nontoxic, highly fluorogenic and biocompatible probe AFN for selective staining of intracellular Lipid Droplets (LDs) in both fixed and live human cervical cancer cells (HeLa) and 3T3-L1 pre-adipocytes without any background artifacts. The salient features of the probe are its visible excitation maximum, aqueous compatibility, selectivity and remarkable stability (for more than a week) in live cells, even better than commercially available Nile red.
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Book Review
DOI: 10.1039/B402142H
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Source Journal
Analyst
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Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
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2,2'-{2,2-Propanediylbis[(2,6-dibromo-4,1-phenylene)oxy]}diethanol
CAS Number:
4162-45-2
Molecular Formula:
C19H20Br4O4
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