Analysis of solvent induced porous PMMA–Bioglass monoliths by the phase separation method – mechanical and in vitro biocompatible studies
Literature Information
D. Durgalakshmi, S. Balakumar
Mimicking three dimensional microstructural scaffolds with their requisite mechanical properties in relation to human bone is highly needed for implant applications. Various biocompatible polymers and bioactive glasses were synthesized to achieve these properties. In the present study, we have fabricated highly porous and bioactive PMMA–Bioglass scaffolds by the phase separation method. Chloroform, acetone and an ethanol–water mixture were used as the different solvent phases in preparing the scaffolds. Large interconnecting pores of sizes ∼100 to 250 μm were observed in the scaffolds and a porosity percentage up to 54% was also achieved by this method. All samples showed a brittle fracture with the highest modulus of 91 MPa for the ethanol–water prepared scaffolds. The bioactivities of the scaffolds were further studied by immersing them in simulated body fluid for 28 days. Scanning electron microscopy, X-ray diffraction and Raman spectra confirmed the formation of bioactive hydroxyl calcium apatite on the surfaces of the scaffolds.
Recommended Journals
Related Literature
Lab on paper: assay of beta-lactam pharmaceuticals by redox titration
Mercy W. Maina, Phelix Makoto Were, Jamie L. Luther, Sarah L. Bliese, Nils Oberhof, Doaa Aldulaimi, Marya Lieberman
DOI: 10.1039/C9AY01547G
Droplet incubation and splitting in open microfluidic channels
Samuel B. Berry, Jing J. Lee, Jean Berthier, Erwin Berthier
DOI: 10.1039/C9AY00758J
The combined detection of ovarian cancer biomarkers HE4 and CA125 by a fluorescence and quantum dot dual-signal immunoassay
Shuange Yao, Wei Xiao, Hui Chen, Yong Tang, Qifang Song, Qubo Zheng, Ning Deng
DOI: 10.1039/C9AY01454C
Facile synthesis of yellow fluorescent carbon dots for highly sensitive sensing of cobalt ions and biological imaging
Min Tian, Yaoming Liu, Yingte Wang, Yong Zhang
DOI: 10.1039/C9AY01244C
Development of an immunochromatographic strip for the detection of rosiglitazone in functional foods based on monoclonal antibodies
Gang Cui
DOI: 10.1039/C9AY01534E
An ultrasensitive electrochemiluminescence biosensor for nuclear factor kappa B p50 based on the proximity hybridization-induced hybridization chain reaction
Xiaocui Huang, Ying Zhang, Wen Xu, Wei Xu, Longhua Guo, Bin Qiu, Zhenyu Lin
DOI: 10.1039/C9CC06210F
Study on the affinity characteristics of proteins on the immobilized metal affinity chromatography column
Rong Li, Peng Chen, Ning Zhang, Bin Chen
DOI: 10.1039/C9AY01469A
A new analytical method for the determination of beta-blockers and one metabolite in the influents and effluents of three urban wastewater treatment plants
Gabriel-Lucian Radu, Roxana Scutariu
DOI: 10.1039/C9AY01597C
You might also like
What are the main uses of 1H-Indazole-6-carbonitrile (CAS: 141290-59-7)?
1H-Indazole-6-carbonitrile finds applications in pharmaceuticals, where it serve...
How should waste containing Dioctyl (2E)-2-butenedioate (CAS: 2997-85-5) be handled?
Waste containing Dioctyl (2E)-2-butenedioate (CAS: 2997-85-5) should be collecte...
What industries use Sodium [(1,2-benzoxazol-3-ylmethyl)sulfonyl]azanide (CAS: 68291-98-5)?
Sodium [(1,2-benzoxazol-3-ylmethyl)sulfonyl]azanide is primarily used in pharmac...
Are there alternatives to Dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-pyridinedicarboxylate (CAS: 741709-66-0) in synthesis?
Dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-pyridinedicarboxyla...
How should waste containing 2-Fluoro-6-hydrazinopyridine (CAS: 80714-39-2) be handled?
Waste containing 2-Fluoro-6-hydrazinopyridine (CAS: 80714-39-2) should be manage...
What is 6-Formyl-2-pyridinecarboxylic acid (CAS: 499214-11-8)?
6-Formyl-2-pyridinecarboxylic acid is an organic compound with the molecular for...
What is the market or research trend for 3-(3,4-dimethoxyphenyl)-2,5-dimethyl-N-(2-morpholin-4-ylethyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS: 900874-91-1)?
Research trends for this compound indicate a focus on its potential applications...
How is 9H-Tribenzo[b,d,f]azepine (CAS: 29875-73-8) typically synthesized?
9H-Tribenzo[b,d,f]azepine is typically synthesized via a multi-step process invo...
How is 1-Cyclopropyl-7-ethoxy-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 1797982-51-4) typically synthesized?
1-Cyclopropyl-7-ethoxy-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxyli...
How should waste containing Methyl 3-oxo-1,2,3,4-tetrahydro-6-quinoxalinecarboxylate (CAS: 671820-52-3) be handled?
Waste containing Methyl 3-oxo-1,2,3,4-tetrahydro-6-quinoxalinecarboxylate (CAS: ...
Source Journal
Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.














