Single-molecule surface-enhanced Raman spectroscopy with nanowatt excitation
Literature Information
Brendan L. Darby, Pablo G. Etchegoin, Eric C. Le Ru
We demonstrate the possibility of single molecule (SM) detection via surface-enhanced Raman spectroscopy (SERS) in two seemingly challenging and unexpected cases: first with ultra-low excitation powers of the order of nanowatts and second in as-synthesized and not deliberately-aggregated silver colloid solution. The experiments are carried out using the bi-analyte method on a methylated form of Rhodamine 6G and one of its isotopologues excited at 514 nm close to the electronic resonance. This study spectacularly highlights the fact that SM-SERS detection is much more common and easier to achieve than typically thought, in particular in the case of resonance Raman excitation. As a result, SM-SERS detection in such cases should not be viewed as an indication of good SERS substrate performance as sometimes implicitly assumed.
Related Literature
Low-temperature synthetic method for size-controlled CdSe nanocrystals: utilization of boron selenide
Nora Iancu, Renu Sharma, Dong-Kyun Seo
DOI: 10.1039/B408702J
Fabrication and photoluminescence of chemically stable La2O3:Eu3+–La2Sn2O7 core–shell-structured nanoparticles
Eiji Hosono, Shinobu Fujihara
DOI: 10.1039/B408495K
A new approach to bioconjugates for proteins and peptides (“pegylation”) utilising living radical polymerisation
François Lecolley, Lei Tao, Giuseppe Mantovani, Ian Durkin, Sylvie Lautru, David M. Haddleton
DOI: 10.1039/B407712A
A regioregular polyalkylthiophene bearing covalently-linked biotin, and its interaction with avidin in solution and in thin films
Fouzi Mouffouk, Simon J. Higgins, Stewart J. Brown, Naser Sedghi, Bill Eccleston, Stuart Reeman
DOI: 10.1039/B408935A
Polystyryl-supported TBD as an efficient and reusable catalyst under solvent-free conditions
Francesco Fringuelli, Ferdinando Pizzo, Carla Vittoriani, Luigi Vaccaro
DOI: 10.1039/B409808K
Photochemical polymerization of thiophene derivatives in aqueous solution
Sergey A. Piletsky, Elena V. Piletska, Kal Karim, Frank Davis, Seamus P. J. Higson, Anthony P. F. Turner
DOI: 10.1039/B408387C
Hierarchical self-assembly in polymeric complexes: Towards functional materials
Olli Ikkala, Gerrit ten Brinke
DOI: 10.1039/B403983A
A C3-symmetric molecular scaffold for the construction of large receptors
Gebhard Haberhauer, Thomas Oeser, Frank Rominger
DOI: 10.1039/B406335J
Optical sensing of amine vapors with a series of tin compounds
Evonne A. Baldauff
DOI: 10.1039/B406230B
Self-oriented pseudoisocyanine J-aggregates in solution
Ken Takazawa, Yasutaka Kitahama, Yasuyuki Kimura
DOI: 10.1039/B409690H
You might also like
What is the market or research trend for N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0)?
N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0) is increasingly being used ...
What precautions should be taken when handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate (CAS: 1050507-06-6)?
When handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate, appropriate p...
What regulatory guidelines apply to diethyldiselane (CAS: 628-39-7)?
Diethyldiselane (CAS: 628-39-7) is classified under the Globally Harmonized Syst...
What is the market or research trend for oxocopper (CAS: 12053-18-8)?
The market for oxocopper (CAS: 12053-18-8) is primarily driven by its use in cat...
What is the market or research trend for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid?
The market for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-c...
What is 2-(1-Pyrrolidinyl)-4-pyridinamine (CAS: 35981-63-6)?
2-(1-Pyrrolidinyl)-4-pyridinamine is a chemical compound with the CAS number 359...
What are the physical and chemical properties of 2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1)?
2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1) is a crystalline sol...
How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?
(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reacti...
What is 3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5)?
3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5) is an organic compound w...
How is Lys-SMCC-DM1 (CAS: 1281816-04-3) typically synthesized?
Lys-SMCC-DM1 is synthesized via a multi-step process involving the coupling of S...
Source Journal
Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.












![1-oxaspiro[4.4]nonan-6-one structure 1-oxaspiro[4.4]nonan-6-one structure](https://static.chemtradehub.com/structs/134/134179-01-4-e051.webp)

