Addressable droplet microarrays for single cell protein analysis
Literature Information
Publication Date
2014-08-06
DOI
10.1039/C4AN01208A
Impact Factor
4.616
Authors
Ali Salehi-Reyhani, Edward Burgin
View Original
Abstract
Addressable droplet microarrays are potentially attractive as a way to achieve miniaturised, reduced volume, high sensitivity analyses without the need to fabricate microfluidic devices or small volume chambers. We report a practical method for producing oil-encapsulated addressable droplet microarrays which can be used for such analyses. To demonstrate their utility, we undertake a series of single cell analyses, to determine the variation in copy number of p53 proteins in cells of a human cancer cell line.
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