Intracellular pH-activated PEG-b-PDPA wormlike micelles for hydrophobic drug delivery
Literature Information
Publication Date
2013-07-16
DOI
10.1039/C3PY00849E
Impact Factor
5.582
Authors
Haijun Yu, Zhiai Xu, Dangge Wang, Xianzhi Chen, Zhiwen Zhang, Qi Yin, Yaping Li
View Original
Abstract
Wormlike micelles with intracellular pH-activating properties were developed. The micelles remained in a “silent” state at physiological pH conditions (i.e. pH 7.4), but were activated in the acidic microenvironment of endocytic vesicles. The wormlike micelles could be employed as nanovectors for the intracellular delivery of hydrophobic drugs for cancer therapy.
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Polymer Chemistry
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8.6
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