pH degradable dendron-functionalized poly(2-ethyl-2-oxazoline) prepared by a cascade “double-click” reaction
Literature Information
Sebla Onbulak, Amitav Sanyal, Richard Hoogenboom
In this study, we report on the synthesis of a dendron-functionalized poly(2-ethyl-2-oxazoline) in a one-pot cascade reaction approach. By means of a bifunctional small organic compound linker, namely (9-azidomethyl)anthracene, alkyne-functionalized PEtOx and maleimide-substituted dendron were coupled in a one-pot cascade approach exploiting the copper-catalyzed azide-alkyne cycloaddition (CuAAC) and the Diels–Alder cycloaddition. The resulting amphiphilic block copolymer was characterized by size-exclusion chromatography (SEC), proton nuclear magnetic resonance (1H NMR) spectroscopy and matrix-assisted laser desorption ionization time-of-flight (MALDI TOF) mass spectrometry (MS). Since the dendron contains acid-labile acetal protecting groups, it is pH responsive and the hydrophilicity significantly increases upon hydrolysis. The aqueous solution behavior and pH-responsivity of the PEtOx–dendron are discussed at neutral pH as well as acidic pH based on dynamic light scattering and fluorescence spectroscopy.
Recommended Journals
Related Literature
Hindrance-functionalized π-stacked polymer based on polystyrene with pendent cardo groups for organic electronics
Cheng-Rong Yin, Yuan Han, Lu Li, Shang-Hui Ye, Wei-Wei Mao, Ming-Dong Yi, Hai-Feng Ling, Ling-Hai Xie, Guang-Wei Zhang
DOI: 10.1039/C3PY21154A
Nucleophilic thiol-Michael chemistry and hyperbranched (co)polymers: synthesis and ring-opening metathesis (co)polymerization of novel difunctional exo-7-oxanorbornenes with in situ inimer formation
Meina Liu, Beng Hoon Tan, Robert P. Burford, Andrew B. Lowe
DOI: 10.1039/C3PY00110E
Using reversibility of the dynamic covalent bond to create porosity in highly ordered polymer thin films under mild conditions and nano-pore functionalization in the gas phase
Jingyi Rao, Anzar Khan
DOI: 10.1039/C3PY00200D
Catalytic Y-tailed amphiphilic homopolymers – aqueous nanoreactors for high activity, low loading SCS pincer catalysts
Joseph P. Patterson, Pepa Cotanda, Elizabeth G. Kelley, Adam O. Moughton, Annhelen Lu, Thomas H. Epps, III, Rachel K. O'Reilly
DOI: 10.1039/C3PY21137A
Synthesis of poly(dithienogermole-2,6-diyl)s
Joji Ohshita, Masayuki Miyazaki, Daiki Tanaka, Yasushi Morihara, Yuki Fujita, Yoshihito Kunugi
DOI: 10.1039/C3PY00253E
New insights into radical and cationic polymerizations upon visible light exposure: role of novel photoinitiator systems based on the pyrene chromophore
Mohamad-Ali Tehfe, Frédéric Dumur, Emmanuel Contal, Bernadette Graff, Fabrice Morlet-Savary, Didier Gigmes, Jean-Pierre Fouassier, Jacques Lalevée
DOI: 10.1039/C2PY20950K
Synthesis of new n-type isoindigo copolymers
François Grenier, Jean-Rémi Pouliot, Hsin-Rong Tseng, Alan J. Heeger, Mario Leclerc
DOI: 10.1039/C2PY20986A
Fully bio-based poly(l-lactide)-b-poly(ricinoleic acid)-b-poly(l-lactide) triblock copolyesters: investigation of solid-state morphology and thermo-mechanical properties
Benoit Gadenne, Carine Alfos
DOI: 10.1039/C3PY00300K
You might also like
What is 1-(2,4,6-Trifluorophenyl)ethanol (CAS: 1250113-83-7)?
1-(2,4,6-Trifluorophenyl)ethanol is an organic compound with the CAS number 1250...
Is 1-(2,4-Dimethoxybenzyl)-4-(hydroxymethyl)-2-pyrrolidinone (CAS: 919111-34-5) safe?
1-(2,4-Dimethoxybenzyl)-4-(hydroxymethyl)-2-pyrrolidinone (CAS: 919111-34-5) is ...
What are the physical and chemical properties of (7S,15R)-6β,15-Diacetoxy-7α,20-epoxy-7-hydroxykaura-2,16-dien-1-one (CAS: 51419-51-3)?
(7S,15R)-6β,15-Diacetoxy-7α,20-epoxy-7-hydroxykaura-2,16-dien-1-one is a crystal...
What regulatory guidelines apply to rac-ethyl (1r,4r)-4-hydroxycyclohexane-1-carboxylate, trans (CAS: 3618-04-0)?
The compound rac-ethyl (1r,4r)-4-hydroxycyclohexane-1-carboxylate, trans (CAS: 3...
What is the market or research trend for 2-(2,4-Difluorophenoxy)-3-nitropyridine (CAS: 175135-62-3)?
The market for 2-(2,4-Difluorophenoxy)-3-nitropyridine (CAS: 175135-62-3) is cur...
What are the main uses of 6-Diazo-5-oxo-L-norleucine (CAS: 157-03-9)?
The main uses of 6-Diazo-5-oxo-L-norleucine (CAS: 157-03-9) include research in ...
What precautions should be taken when handling 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (CAS: 173308-19-5)?
When handling 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (CAS: 173308-19-5), i...
How is 5-Methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS: 178488-37-4) typically synthesized?
5-Methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS: 178488-37-4) can be synthesi...
Are there alternatives to 2,4,6-Trihydroxyisophthalaldehyde (CAS: 4396-13-8) in synthesis?
There are alternative reagents that can be used in the synthesis of 2,4,6-Trihyd...
What is (2Z)-3-(5-Fluoro-1H-indol-3-yl)-2-sulfanylacrylic acid (CAS: 179461-52-0)?
(2Z)-3-(5-Fluoro-1H-indol-3-yl)-2-sulfanylacrylic acid is a chemical compound wi...
Source Journal
Polymer Chemistry

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.














