Synthesis, assembly, and cross-linking of polymeramphiphilesin situ: polyurethane–polylactide core–shell particles
Literature Information
Kevin P. McNamee, Louis M. Pitet, Daniel M. Knauss
Core–shell polymeric particles consisting of biodegradable polylactide (PLA) arms emanating from a crosslinked polyurethane (PU) core were prepared in situ by a polymerization induced phase separation strategy. Sub-micron sized particles were spawned in dilute solution during polyurethane formation with simultaneous incorporation of end-functional PLA macromonomers. The inherent incompatibility of PU with PLA was shown to induce micelle formation during core-crosslinking. The versatility of this method with respect to size characteristics was demonstrated by employing a variety of PLA–PU ratios. Electron microscopy was used to visualize the particle dispersions in organic solvents. The average size characteristics were measured by dynamic light scattering. Collectively, the initial ratio of PU precursor to PLA as well as the PLA chain length were shown to influence the resulting particle size characteristics. This simple preparation method combined with a biodegradable, biocompatible shell should be amenable to further functionalization and it carries the potential to encapsulate components intended for drug delivery, for example.
Related Literature
Electrodeposition of monodispersed Fe nanocrystals from an ionic liquid
C. L. Aravinda, W. Freyland
DOI: 10.1039/B409861G
Novel Pt/CeO2/C catalysts for electrooxidation of alcohols in alkaline media
Changwei Xu, Pei Kang Shen
DOI: 10.1039/B408589B
Synthesis and characterization of electron-rich nickel tris-carbene complexes‡
Xile Hu, Ingrid Castro-Rodriguez, Karsten Meyer
DOI: 10.1039/B409241D
A thermally stable nanoporous nickel 5-sulfoisophthalate; crystal structure and adsorption properties
Dae Sung Kim, Paul M. Forster, Ronan Le Toquin, Anthony K. Cheetham
DOI: 10.1039/B408535C
Bis(diethylamino)carbene and the mechanism of dimerisation for simple diaminocarbenes
Roger W. Alder, Leila Chaker, François P. V. Paolini
DOI: 10.1039/B409112D
A samarium cyclooctatetraene complex as catalyst for hydroamination/cyclisation catalysis
Agustino Zulys, Tarun K. Panda, Michael T. Gamer, Peter W. Roesky
DOI: 10.1039/B410918J
First lanthanide dipolar complexes for second-order nonlinear optics
Katell Sénéchal, Loïc Toupet, Isabelle Ledoux, Joseph Zyss, Hubert Le Bozec, Olivier Maury
DOI: 10.1039/B407073A
Ionic hydrogenation of C-20, 22-ketene dithioacetal: stereoselective synthesis of steroidal C (20R) aldehydes
Bapurao B. Shingate, Braja G. Hazra, Vandana S. Pore, Rajesh G. Gonnade, Mohan M. Bhadbhade
DOI: 10.1039/B407952C
Role of pore curvature on the thermal stability of gold nanoparticles in mesoporous silica
Mangesh T. Bore, Hien N. Pham, Timothy L. Ward, Abhaya K. Datye
DOI: 10.1039/B407575G
An unprecedented intramolecular coupling of o-carboranyl and cyclopentadienyl. Synthesis and structural characterization of a ruthenium complex containing a novel doubly-bridged cyclopentadienyl-carboranyl ligand
Yi Sun, Hoi-Shan Chan, Pierre H. Dixneuf, Zuowei Xie
DOI: 10.1039/B409772F
You might also like
What is 1-(2,4,6-Trifluorophenyl)ethanol (CAS: 1250113-83-7)?
1-(2,4,6-Trifluorophenyl)ethanol is an organic compound with the CAS number 1250...
Is 1-(2,4-Dimethoxybenzyl)-4-(hydroxymethyl)-2-pyrrolidinone (CAS: 919111-34-5) safe?
1-(2,4-Dimethoxybenzyl)-4-(hydroxymethyl)-2-pyrrolidinone (CAS: 919111-34-5) is ...
What are the physical and chemical properties of (7S,15R)-6β,15-Diacetoxy-7α,20-epoxy-7-hydroxykaura-2,16-dien-1-one (CAS: 51419-51-3)?
(7S,15R)-6β,15-Diacetoxy-7α,20-epoxy-7-hydroxykaura-2,16-dien-1-one is a crystal...
What regulatory guidelines apply to rac-ethyl (1r,4r)-4-hydroxycyclohexane-1-carboxylate, trans (CAS: 3618-04-0)?
The compound rac-ethyl (1r,4r)-4-hydroxycyclohexane-1-carboxylate, trans (CAS: 3...
What is the market or research trend for 2-(2,4-Difluorophenoxy)-3-nitropyridine (CAS: 175135-62-3)?
The market for 2-(2,4-Difluorophenoxy)-3-nitropyridine (CAS: 175135-62-3) is cur...
What are the main uses of 6-Diazo-5-oxo-L-norleucine (CAS: 157-03-9)?
The main uses of 6-Diazo-5-oxo-L-norleucine (CAS: 157-03-9) include research in ...
What precautions should be taken when handling 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (CAS: 173308-19-5)?
When handling 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (CAS: 173308-19-5), i...
How is 5-Methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS: 178488-37-4) typically synthesized?
5-Methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS: 178488-37-4) can be synthesi...
Are there alternatives to 2,4,6-Trihydroxyisophthalaldehyde (CAS: 4396-13-8) in synthesis?
There are alternative reagents that can be used in the synthesis of 2,4,6-Trihyd...
What is (2Z)-3-(5-Fluoro-1H-indol-3-yl)-2-sulfanylacrylic acid (CAS: 179461-52-0)?
(2Z)-3-(5-Fluoro-1H-indol-3-yl)-2-sulfanylacrylic acid is a chemical compound wi...
Source Journal
Polymer Chemistry

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.














