Fabrication of Cr doped SnO2 nanoparticles based biosensor for the selective determination of riboflavin in pharmaceuticals

Literature Information

Publication Date 2013-01-09
DOI 10.1039/C3AN36754A
Impact Factor 4.616
Authors

N. Lavanya, S. Radhakrishnan, M. Navaneethan, Y. Hayakawa


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Abstract

We report the fabrication and testing of a riboflavin (RF) biosensor based on the use of Cr doped SnO2 nanoparticles. The Cr–SnO2 nanoparticles with chromium concentration from 0 to 5 wt% were synthesised by a microwave irradiation method. Magnetic studies revealed that only 3 wt% Cr doped nano-SnO2 has ferromagnetic behaviour at room temperature. This Cr–SnO2 nanoparticles modified electrode responded to RF linearly over a concentration range of 0.2 × 10−6 to 1.0 × 10−4 M with a detection limit of 107 nM. The fabricated sensor showed an excellent anti-interference ability against electroactive species and metal ions and proved to be useful for the estimation of the RF content in pharmaceutical samples with satisfactory recovery.

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